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5FU-Gls 500 Injection
Prescription Required
Product introduction
5FU-Gls 500 Injection is used in the treatment of cancers of stomach, colon, rectum, breast, and lungs. It may be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
5FU-Gls 500 Injection is given as injection under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include increased risk of infection, mouth ulcer, vomiting, weakness, and nausea. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
5FU-Gls 500 Injection is given as injection under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include increased risk of infection, mouth ulcer, vomiting, weakness, and nausea. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of 5FU-Gls Injection
Benefits of 5FU-Gls Injection
In Cancer
5FU-Gls 500 Injection helps to treat certain kinds of cancer such as cancer of the breasts, lungs, colon, rectum etc. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. 5FU-Gls 500 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of 5FU-Gls Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of 5FU-Gls
- Nausea
- Vomiting
- Hair loss
- Diarrhea
- Bronchospasm
- Infection
- Myelosuppression
- Agranulocytosis (deficiency of granulocytes in the blood)
- General discomfort
- Itching
- Skin exfoliation
- Anemia (low number of red blood cells)
- Febrile neutropenia
- Angina (heart related chest pain)
- ECG changes
- Decreased immunity
How to use 5FU-Gls Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How 5FU-Gls Injection works
5FU-Gls 500 Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with 5FU-Gls 500 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
5FU-Gls 500 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
5FU-Gls 500 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
5FU-Gls 500 Injection may cause side effects which could affect your ability to drive.
5FU-Gls 500 Injection can cause side effects such as nausea and can also produce adverse events on your nervous system which cause visual changes.This may affect your ability to drive.
5FU-Gls 500 Injection can cause side effects such as nausea and can also produce adverse events on your nervous system which cause visual changes.This may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
5FU-Gls 500 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of 5FU-Gls 500 Injection may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
5FU-Gls 500 Injection should be used with caution in patients with liver disease. Dose adjustment of 5FU-Gls 500 Injection may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
5FU-Gls 500 Injection
₹24.0/Injection
Florac 500mg Injection
Cadila Pharmaceuticals Ltd
₹21.26/injection
11% cheaper
Kucil 500mg Injection
Khandelwal Laboratories Pvt Ltd
₹20.96/injection
13% cheaper
5FU Cbc 500mg Injection
Chandra Bhagat Pharma Pvt Ltd
₹23/injection
4% cheaper
Fivoflu 500mg Injection
Fresenius Kabi India Pvt Ltd
₹23.07/injection
4% cheaper
Chemoflura 500mg Injection
Neon Laboratories Ltd
₹27.5/injection
15% costlier
Quick tips
- 5FU-Gls 500 Injection helps treat cancers of stomach, colon, rectum, breast, and lungs.
- It is given as an injection into a vein, or as a drip (infusion) into a vein or artery.
- The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
- It may cause dizziness and visual changes. Do not drive or do anything requiring concentration until you know how it affects you.
- Your doctor may regularly monitor your blood cells and liver function during treatment with this medicine.
Fact Box
Chemical Class
Pyrimidine Analog
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Patient concerns
FAQs
Is fluorouracil a vesicant?
No, fluorouracil is not a vesicant (irritant).
Is fluorouracil safe?
Fluorouracil is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Is fluorouracil a steroid?
No, flurouracil is not a steroid.
Is fluorouracil cream chemotherapy?
Fluorouracil is used as chemotherapy for the treatment of cancers.
Is fluorouracil cream for warts?
Yes, fluorouracil is used for the treatment of warts.
Is fluorouracil the same as efudex?
Efudex is a brand name (trade name) for fluorouracil.
Does fluorouracil affect normal skin?
Fluorouracil has minimal effect on the surrounding healthy skin.
Does fluorouracil cause hair loss?
Yes, fluorouracil may cause temporary hair loss.
Does fluorouracil cause scarring?
No, fluorouracil is not known to cause scarring.
Does fluorouracil cause headaches?
Though headache is not a common side effect of fluorouracil, it may occur uncommonly is some people.
Why does fluorouracil cause fatigue?
As with any chemotherapy for cancer, fluorouracil causes fatigue which is attributed to be of multi-factor origin, but inflammation and anemia are thought to be the most important factors.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 946-47.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 561-63.
- Fluorouracil. Hurley, Maidenhead: Hospira UK Ltd.; 1985 [revised Jan. 2017]. [Accessed 29 Jan. 2019] (online) Available from:
- Drugs.com. Fluorouracil Pregnancy and Breastfeeding Warnings. [Accesses on 27 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Fluorouracil. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Country of origin: India
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₹24
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10.0 ml in 1 ampoule
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