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M.Pharm, MBBS
Last updated
26 Nov 2023 | 12:00 AM (IST)

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Abirakast 250mg Tablet

Prescription Required

Product introduction

Abirakast 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Abirakast 250mg Tablet is used to treat various types of cancer

Uses of Abirakast Tablet


Side effects of Abirakast Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Abirakast

  • Edema (swelling)
  • Vomiting
  • Decreased potassium level in blood
  • Decreased white blood cell count
  • Fatigue
  • Increased liver enzymes
  • Anemia (low number of red blood cells)
  • Urinary tract infection
  • Diarrhea
  • High blood pressure
  • Cough
  • Hypercholesterolemia (high cholesterol)
  • Joint swelling
  • Increased levels of blood fat
  • Altered blood sugar level

How to use Abirakast Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abirakast 250mg Tablet is to be taken empty stomach.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Abirakast 250mg Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Abirakast 250mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Abirakast 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Abirakast 250mg Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Abirakast 250mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Abirakast 250mg Tablet is recommended.
Because of the limited information, cautious use of Abirakast 250mg Tablet is recommended in patients with severe kidney disease.
Liver
CAUTION
Abirakast 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Abirakast 250mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Abirakast 250mg Tablet
₹162.5/Tablet
Zelgor 250mg Tablet
Sun Pharmaceutical Industries Ltd
₹54.17/tablet
67% cheaper
Abirapro 250mg Tablet
Glenmark Pharmaceuticals Ltd
₹233.33/tablet
44% costlier
₹162.5/tablet
same price
₹162.5/tablet
same price
Zytiga 250mg Tablet
Janssen Pharmaceuticals
₹1250/tablet
669% costlier

Quick tips

  • Abirakast 250mg Tablet treats prostate cancer that has spread to other parts of the body.
  • It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
  • It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.
  • Always use effective birth control measures to prevent pregnancy while taking this medicine.
  • Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

Fact Box

Chemical Class
Androstene Derivative
Habit Forming
No
Therapeutic Class
abcde
Action Class
Anticancer-others

Patient concerns

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Dr. Sir, I have facing depression again after 2 year , and I don't know what was it's triggered point. Kindly tell me what should i do in this situation, I am bachelor. Is Zyven is good for this situation as it was earlier suggest by psychiatrist.
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
Hysterectomy ovaries removed body ache night sweats
Dr. Megha Gupta
Obstetrics and Gynaecology
Such problems are common after getting ovaries removed. Do not worry, these problems will eventually fade with time. However if it causes discomfort and restlessness, you should see your gynaecologist for hormonal replacement therapy
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FAQs

Can Abirakast 250mg Tablet cure prostate cancer?

Abirakast 250mg Tablet does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Abirakast 250mg Tablet then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Abirakast 250mg Tablet.

Is Abirakast 250mg Tablet a chemotherapy drug?

Abirakast 250mg Tablet is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Abirakast 250mg Tablet stops your body from making testosterone. This can slow down the growth of prostate cancer.

Why do I need to take prednisolone with Abirakast 250mg Tablet?

Your doctor will always prescribe prednisolone with Abirakast 250mg Tablet. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Abirakast 250mg Tablet.

Does Abirakast 250mg Tablet affect liver?

Abirakast 250mg Tablet can cause severe liver problems. In very rare cases, Abirakast 250mg Tablet may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.

How frequently should the liver investigations be done?

Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Abirakast 250mg Tablet.

How to take Abirakast 250mg Tablet?

Abirakast 250mg Tablet should be taken on an empty stomach with water 1 hour before eating or at least 2 hours after eating. Taking it with food may cause increased and variable levels of Abirakast 250mg Tablet in your blood which can be harmful. Remember not to crush or chew the tablet.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
  2. Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Aprazer Healthcare Pvt Ltd
Address: 36-B, Pusa Rd, Block 11, Old Rajinder Nagar, Rajinder Nagar, New Delhi, Delhi 110060
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

MRP
19500
Inclusive of all taxes
120.0 tablets in 1 bottle
SOLD OUT
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Same salt composition:Abiraterone Acetate (250mg)
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