Actibile 600 SR Tablet is used to dissolve certain gallstones and prevent them from forming. It is also used to treat a type of liver disease called primary biliary cirrhosis. It helps break down the cholesterol that has converted into stones in your gallbladder thereby dissolving the stones.

Actibile 600 SR Tablet is used to restore the function of the liver.

Uses of Actibile Tablet SR

Treatment of Primary biliary cirrhosis
Treatment of Gallbladder stones

Benefits of Actibile Tablet SR

In Treatment of Primary biliary cirrhosis

Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Actibile 600 SR Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

In Treatment of Gallbladder stones

Actibile 600 SR Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

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Side effects of Actibile Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actibile

Abdominal pain
Diarrhea
Hair loss
Itching
Nausea
Rash

How to use Actibile Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actibile 600 SR Tablet is to be taken with food.

How Actibile Tablet SR works

Actibile 600 SR Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Safety advice

Alcohol

UNSAFE

Actibile 600 SR Tablet may cause excessive drowsiness with alcohol.

Pregnancy

SAFE IF PRESCRIBED

Actibile 600 SR Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Actibile 600 SR Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Actibile 600 SR Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Actibile 600 SR Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Actibile 600 SR Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Actibile 600 SR Tablet

₹42.1/Tablet SR

Ursocol SR 600 Tablet

Sun Pharmaceutical Industries Ltd

₹26.1/tablet sr

38% cheaper

Uda 600mg Tablet SR

Tas Med India Pvt Ltd

₹63.1/tablet sr

50% costlier

Udicare 600 SR Tablet

Care Formulation Labs Pvt Ltd

₹78.1/tablet sr

86% costlier

Ursolid 600mg Tablet SR

₹51.5/tablet sr

22% costlier

Urmocol SR 600 Tablet

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₹49.5/tablet sr

18% costlier

Quick tips

Actibile 600 SR Tablet should be taken after a meal with a glass of milk or water.
Eat a healthy diet, exercise regularly, and avoid alcohol intake.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter.
Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class

Bile Acids and Salts

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotectives

Patient concerns

Im pregnant with 8months and having itching in whole body. OT/PT is little higher. Tak Im taking Actibile 300. Prescribed by My doctor. Do I need to consult gastro. This is my second issue. In 1st issue I had same problem. Ans as soon as i delivered baby this all disappeared. Please suggest what to do

Dr. Dharna Gupta

Obstetrics and Gynaecology

Take actibile twice daily.use lactocalamine lotion.No need for gaatro consultYou can take tab cetrizine if itching is too muchFollow your OBS advice

Gallbladder Stones giving. Patient is having asthama

Dr. Praveen Pushkar

Urology

Consult g i surgeon

User feedback

Patients taking Actibile 600 SR Tablet

Twice A Day

62%

Once A Day

33%

Alternate Day

FAQs

Q. When should I take Actibile 600 SR Tablet?

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Actibile 600 SR Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.

Q. Is Actibile 600 SR Tablet safe?

Actibile 600 SR Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

Q. How does Actibile 600 SR Tablet help the liver?

Actibile 600 SR Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Q. Does Actibile 600 SR Tablet cause weight gain?

Yes, there is a chance of weight gain with Actibile 600 SR Tablet, but it is not common. The use of Actibile 600 SR Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.

Q. What should I avoid while taking Actibile 600 SR Tablet?

While taking Actibile 600 SR Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Actibile 600 SR Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Actibile 600 SR Tablet. So, ask your doctor about the time gap that should be maintained between Actibile 600 SR Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Actibile 600 SR Tablet.

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Related lab tests

Liver Function Test

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Ursodiol. Birmingham, Alabama: Axcan Pharma US, Inc.; 1997 [revised Nov. 2009]. [Accessed 25 Jan. 2019] (online) Available from:
Ursodiol. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 1997 [revised Jun. 2013]. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Ursodeoxycholic [Package Insert]. Mumbai, India: Alkem Laboratories Ltd.; 2016. [Accessed 07 Aug. 2023]. (online) Available from:
The Lancet. Gastroenterology and Hepatology. [Accessed 07 Aug. 2023]. (online) Available from:

Marketer details

Name: Zydus Cadila

Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Actibile 600 SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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