Afatin 40mg Tablet is used in the treatment of non-small cell lung cancer. It is used in the treatment of adult patients who have certain mutations of epidermal growth factor receptor (EGFR).

Afatin 40mg Tablet is used to treat different types of cancer

Uses of Afatin Tablet

Non-small cell lung cancer

Benefits of Afatin Tablet

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Afatin 40mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Afatin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Afatin

Diarrhea
Rash
Dry skin
Nausea
Vomiting
Loss of appetite
Itching
Stomatitis (Inflammation of the mouth)
Nail disorder

How to use Afatin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afatin 40mg Tablet is to be taken empty stomach.

How Afatin Tablet works

Afatin 40mg Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (EGFR, HER2, and HER4) that are responsible for the growth of cancer cells. Hence, resulting in the downregulation of signaling pathways. This is how it to stop or slow the spread of cancer.

Safety advice

Alcohol

SAFE

Consuming alcohol with Afatin 40mg Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Afatin 40mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Afatin 40mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Afatin 40mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Afatin 40mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Afatin 40mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Afatin 40mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Afatin 40mg Tablet may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Afatin 40mg Tablet

₹225.0/Tablet

Xovoltib 40mg Tablet

Boehringer Ingelheim

₹2106.75/tablet

886% costlier

Afanat 40 Tablet

Natco Pharma Ltd

₹197.7/tablet

8% cheaper

Afmed 40mg Tablet

Medicamen Biotech Ltd

₹202.46/tablet

5% cheaper

Afamac 40 Tablet

Admac Pharma Ltd

₹214.25/tablet

same price

Afadel 40mg Tablet

Adley Formulations

₹72.6/tablet

66% cheaper

Quick tips

You have been prescribed Afatin 40mg Tablet for the treatment of certain type of lung cancer (non-small cell lung cancer).
Take Afatin 40mg Tablet on an empty stomach at least 1 hour before a meal or 2 hours after a meal.
Diarrhea is common with Afatin 40mg Tablet and may sometimes be severe. Your doctor may prescribe medicines to treat diarrhea. Stay hydrated and take this medicine exactly as directed.
Afatin 40mg Tablet can make your skin sensitive to the sun. Limit your time in the sun. Use sunscreen and wear protective clothing if you have to be in sunlight.
Afatin 40mg Tablet can cause redness, rash, and acne. Get treatment for skin reactions as soon as you notice them.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Quinazoline and Butenamide Derivative

Habit Forming

Therapeutic Class

abcde

Action Class

Tyrosine kinase inhibitors

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

Right lung tumour cancer in upper portion In jalgaon district which oncologist is best for lung cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Dr Nitin Chaudhari us best oncologist

My father in law is a lung cancer patient.He had gone through two chemo cycles.The first one led to a significant reduction of about 50% in the tumor size.He was administered gemcitabine and carboplatin.However,the 2nd one was ineffective.Please advise as to what could be the next course of action. He was a smoker and has non-small cell carcinoma.The cancer has spread to the adrenal glands.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

U have to do a CT SCAN 3WKS AFTER 3RD CHEMOBased on that u make assessment of response

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References

Afatinib. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2013. [Accessed 03 Jul. 2019] (online) Available from:
Gilotrif. Afatinib. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: BDR Pharmaceuticals Internationals Pvt

Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.