Antigrain Tablet is a medicine used to prevent and treat migraine. It blocks the release of certain chemical messengers that cause pain and inflammation. It also blocks the signals in the brain that cause nausea and vomiting associated with migraine.

Antigrain Tablet is a combination of adenosine receptor (A1 & A2) antagonist, ergot derivative, analgesic & antipyretic-PCM, and dopamine (D2) receptor antagonist-prochlorperazine.

Uses of Antigrain Tablet

Migraine

Benefits of Antigrain Tablet

In Migraine

Antigrain Tablet is a combination of medicines that treat and prevent migraine headaches. It changes the electrical activity in the brain, blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. It also contains caffeine that stimulates your brain to uplift your mood and give you a feeling of well being by improving your energy levels. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Antigrain Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Antigrain

Sedation
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Drowsiness
Urinary retention
Dryness in mouth
Increased heart rate
Constipation
Muscle pain

How to use Antigrain Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Antigrain Tablet is to be taken with food.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Antigrain Tablet.

Pregnancy

UNSAFE

Antigrain Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Antigrain Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Occasional short-term use of Antigrain Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Driving

UNSAFE

Antigrain Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Antigrain Tablet should be used with caution in patients with kidney disease. Dose adjustment of Antigrain Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Antigrain Tablet should be used with caution in patients with liver disease. Dose adjustment of Antigrain Tablet may be needed. Please consult your doctor.

What if you forget to take Antigrain Tablet?

If you miss a dose of Antigrain Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Antigrain Tablet

₹6.35/Tablet

Vasograin Tablet

Cadila Pharmaceuticals Ltd

₹8.05/tablet

27% costlier

NT Grain Tablet

Intas Pharmaceuticals Ltd

₹4.05/tablet

36% cheaper

Neuromol Plus Tablet

Bilcare Ltd

₹2.8/tablet

56% cheaper

Migraneck Tablet

Leeford Healthcare Ltd

₹28.5/tablet

349% costlier

Livigrain Tablet

Lividus Pharmaceuticals Pvt Ltd

₹5/tablet

21% cheaper

View all substitutes

Quick tips

Antigrain Tablet

Antigrain Tablet helps in the treatment and prevention of migraine headaches.
Do not take it to treat an acute attack of migraine.
Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get sufficient sleep and avoid stress
It should be taken at night-time before going to bed.
It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Antigrain Tablet affects you.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Do not stop taking the medication suddenly as it can cause worsening of headaches.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)

Dr. Faran Siddiqui

Homeopathy

Migraine and headache are two different things migraine is primarily headache of one side in symmetrically

Some time at a sudden Strong half headache pain in left side and also left eye tearing Please consult me

Dr. Pushkar Mani

Physician

it could be migraine

FAQs

Antigrain Tablet

Q. What is Antigrain Tablet?

Antigrain Tablet is a combination of four medicines: Paracetamol, Ergotamine, Caffeine and Prochlorperazine. This medicine is used in the treatment of migraine symptoms like a headache, nausea and vomiting. Ergotamine prevents blood vessels in the head from expanding. Caffeine increases the absorption of ergotamine and also narrows the widened blood vessels. Paracetamol blocks the release of certain chemical messengers in the brain that causes pain. Prochlorperazine is an antiemetic which prevents vomiting by blocking signals to the part of your brain that cause nausea/vomiting.

Q. What can cause or trigger a migraine attack?

Certain physical or environmental factors, such as foods, hormonal changes, weather and stress can lead to or “trigger” a migraine. However, it is important to remember that triggers can be different for everyone. That is why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones do not. Keeping a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.

Q. Can I stop taking Antigrain Tablet when my migraine symptoms are relieved?

Antigrain Tablet is usually used for prevention and treatment of migraine attack. Antigrain Tablet should be continued as advised by the doctor.

Q. Can the use of Antigrain Tablet cause constipation?

Yes, the use of Antigrain Tablet can cause constipation. Lifestyle changes like eating a good amount of high-fiber foods such as fresh fruits, vegetables and cereals, drinking plenty of water or other fluids and regular exercise can help relieve constipation.

Q. Can the use of Antigrain Tablet cause dry mouth?

Yes, the use of Antigrain Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Antigrain Tablet can increase the risk of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended dose of this medicine, please consult your doctor for re-evaluation.

Q. Does Antigrain Tablet expire?

Yes, Antigrain Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Antigrain Tablet after the expiry date.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Tulane University: School of Medicine. Caffeine. [Accessed 29 Jan. 2019] (online) Available from:
Drugs.com. Ergotamine. [Accessed 24 Apr. 2019] (online) Available from:
Prochlorperazine maleate. Skipton, UK: Dales Pharmaceuticals Limited; 2016. [Accessed 28 Mar. 2019] (online) Available from:

Marketer details

Name: Ikon Remedies Pvt Ltd

Address: near axis bank, amrawati road, wadi,nagpur-440 023 (maharashtra) india

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.