Closin 50mg Tablet is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave).

Closin 50mg Tablet is used to treat schizophrenia and Parkinson's disease (a disorder of the nervous system that causes difficulties with movement and balance) in whom other medicines have not worked.

Uses of Closin Tablet

Schizophrenia

Benefits of Closin Tablet

In Schizophrenia

Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Closin 50mg Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Closin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Closin

Dizziness
Fainting
Constipation
Fever
Weight gain
Decreased white blood cell count
Extrapyramidal symptoms
Increased liver enzymes
Drowsiness
Seizure
Increased white blood cell count (eosinophils)
Anticholinergic effects
Tachycardia
Excessive salivation

How to use Closin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Closin 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Closin 50mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Closin 50mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Closin 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If Closin 50mg Tablet is used, monitor the baby for excessive sedation. Periodically, keep a check on the baby's white blood cell count as well.

Driving

UNSAFE

Closin 50mg Tablet may cause side effects which could affect your ability to drive.
You may feel tired, drowsy, dizzy or you may feel faint while taking ClozapineClosin 50mg Tablet, especially during the early stages of treatment. This may affect your driving ability.

Kidney

CAUTION

Closin 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Closin 50mg Tablet may be needed. Please consult your doctor.
Use of Closin 50mg Tablet is may not be advised in patients with severe kidney disease.

Liver

CAUTION

Closin 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Closin 50mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable. Inform your doctor if you experience nausea, vomiting and/or weight loss while taking this medicine.

What if you forget to take Closin Tablet?

If you miss a dose of Closin 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Closin 50mg Tablet

₹5.46/Tablet

Sizopin 50 Tablet

Sun Pharmaceutical Industries Ltd

₹2.7/tablet

51% cheaper

Skizoril 50mg Tablet

Intas Pharmaceuticals Ltd

₹5.4/tablet

1% cheaper

Lozapin 50mg Tablet

Torrent Pharmaceuticals Ltd

₹5.36/tablet

2% cheaper

Alkepin Odt 50mg Tablet

Alkem Laboratories Ltd

₹5.39/tablet

1% cheaper

Zaporil 50mg Tablet

Icon Life Sciences

₹5/tablet

8% cheaper

View all substitutes

Quick tips

Closin 50mg Tablet helps treat schizophrenia in people for whom other medicines are ineffective or not tolerated.
Take it with or without food, preferably at the same time everyday.
It can cause dizziness and sleepiness. Be cautious while driving or doing anything that requires concentration.
It may cause low blood pressure and dehydration. Drink plenty of fluids and rise slowly from a sitting or lying position.
It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Do not stop taking Closin 50mg Tablet without talking to your doctor first as it may cause worsening of symptoms.

Fact Box

Chemical Class

Dibenzodiazepine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

Patient concerns

Suffering Schizophrnia from last 20+ years. Is cure able ?

Dr. Ambrish Dharmadhikari

Psychiatry

We are here to helpSchizophrenia is chronic disorderSymptoms can be stopped from expressingCure is difficult word to say in schizophrenia

Suffering from schizophrenia . What to do

Dr. Mehtab Baig

Orthopaedic Physiotherapy

contacts your neurophysician or neuro psychtrist or some of meditation or exercises contact my clinic because of,this type of patient differ from others

suffering from schizophrenia plz help

Dr. Jyoti Kapoor Madan

Psychiatry

Schizophrenia is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by fear, odd experiences and distorted thought pattern. Treatment is with antipsychotic medicines which may need to continue throughout life. Coping with a mental disorder as serious as schizophrenia can be challenging, both for the person with the condition and for friends and family. Here are some ways to cope: 1. Learn about schizophrenia. Education about the disorder can help motivate the person with the disease to stick to the treatment plan. Education can help friends and family understand the disorder and be more compassionate with the person who has it. 2. Join a support group. Support groups for people with schizophrenia can help them reach out to others facing similar challenges. Support groups may also help family and friends cope. 3. Stay focused on goals. Managing schizophrenia is an ongoing process. Keeping treatment goals in mind can help the person with schizophrenia stay motivated. Help your loved one remember to take responsibility for managing the illness and working toward goals. 4. Ask about social services assistance. These services may be able to assist with affordable counselling services, job placements and other daily activities. 5. Learn relaxation and stress management. The person with schizophrenia and loved ones may benefit from stress-reduction techniques such as meditation, yoga or tai chi. Please see a psychiatrist for further guidance.

FAQs

Q. How long does it take for Closin 50mg Tablet to work?

Like many medicines, Closin 50mg Tablet does not work straight away. You might start feeling more calm and relaxed after a few weeks of taking this medicine.

Q. Why has Closin 50mg Tablet been prescribed?

Closin 50mg Tablet is an antipsychotic drug used to treat manic episodes and Schizophrenia, a mood disorder. It shortens the time to recovery and prevents mania from returning. It is also used to reduce the risk of suicidal behavior in people with Schizophrenia.

Q. Does Closin 50mg Tablet help with anxiety?

Yes, Closin 50mg Tablet helps calm the mind and decreases the level of anxiety and aggressive behavior in patients with Schizophrenia.

Q. Is Closin 50mg Tablet addictive?

No, Closin 50mg Tablet is not addictive in nature. No habit-forming potential has been seen with its use. However, always follow your doctor's advice regarding the duration of its use.

Q. When should I see my doctor?

Seek immediate medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction, pain or burning when you urinate, or vaginal itching or discharge.

Q. Can Closin 50mg Tablet cause dizziness?

Yes. Closin 50mg Tablet can cause dizziness by reducing blood pressure. If this happens to you, you should sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while traveling.

Q. Why do I have to have regular blood tests while I am taking Closin 50mg Tablet?

Closin 50mg Tablet is known to cause a rare but serious side effect called “agranulocytosis”. This side effect occurs in less than 1 out of every 100 people who take this medicine. This side effect can result in a decrease in the number of white blood cells (infection-fighting cells) in your body. Without enough white blood cells, your body may not be able to. In order to prevent this, your doctor may prescribe you a blood test to check your white blood cell count.

Q. Can I drink alcohol while taking Closin 50mg Tablet?

It is recommended that people taking this medicine should not drink alcohol. This is because Closin 50mg Tablet is an antipsychotic and taking it with alcohol can cause severe drowsiness. This can lead to falls and accidents. Also, drinking alcohol may make mania, depression, and anxiety worse. Discuss any concerns you have with your doctor, pharmacist, or nurse.

Q. I am experiencing a change in my taste after the start of the treatment with Closin 50mg Tablet. Any tips to reduce it?

A change in taste is a common side-effect of this medicine. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You may also add some extra flavor or seasonings to your food.

Q. I am having trouble remembering to take my medications. Is there anything I can do to help me remember?

In order to avoid missing a dose, use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member a friend to remind you or check in with you to be sure you are taking your medication.

Q. What happens if I stop taking Closin 50mg Tablet?

It is advisable not to stop taking this medicine without talking to your doctor, since it may worsen your symptoms. Your doctor will probably want to decrease your dose gradually.

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Top Psychiatrists

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Dr. Jyoti Kapoor Madan

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Clozapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 153-59.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 308-309.
Clozapine. Potters Bar, Hertfordshire: Mylan Products Limited; 1989 [revised Dec. 2018]. [Accessed 22 Jan. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
Clozapine. East Hanover, New Jersey: Novartis Pharmaceuticals; 2004. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

Marketer details

Name: S P Pharma

Address: 5404, street no. 3 new shivaji nagar, Hargobind marg, Ludhiana, 141008-Ludhiana

Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Closin 50mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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