Combither 20mg/120mg Tablet is used for the treatment of malaria in both children and adults. It contains two medicines both of which belong to a group of medicines called antimalarials. However, it is not used to prevent malaria or to treat severe/complicated malaria (when the brain, lungs, or kidneys are affected).

Combither 20mg/120mg Tablet is a combination of two antiparasitic medicines: Combither 20mg/120mg Tablet1 and Combither 20mg/120mg Tablet2 which treat malaria.

Uses of Combither Tablet

Treatment of Malaria

Benefits of Combither Tablet

In Treatment of Malaria

Malaria is an infection that is transmitted by mosquito bites. Combither 20mg/120mg Tablet effectively treats malaria by killing the malarial parasites. However, it should not be used to prevent malaria and should be taken only when prescribed by a doctor. This medicine makes you feel better within a few days of treatment. But, if you have fever, chills, muscle pain, or headache soon after you finish your treatment, this could be a sign that you still are infected with malaria. Consult your doctor immediately if you notice any such symptoms.

Refrain from taking any other medicines or antacids along with this medicine (unless advised by the doctor) as they may affect the absorption of this medicine. Do not use this medicine for treating any other condition without consulting your doctor.

Side effects of Combither Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combither

Headache
Loss of appetite
Dizziness
Weakness
Joint pain
Muscle pain

How to use Combither Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combither 20mg/120mg Tablet is to be taken with food.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Combither 20mg/120mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Combither 20mg/120mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Combither 20mg/120mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Combither 20mg/120mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Combither 20mg/120mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combither 20mg/120mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with severe kidney disease.

Liver

CAUTION

Combither 20mg/120mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Combither 20mg/120mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Combither 20mg/120mg Tablet

₹12.12/Tablet

Lumerax 20mg/120mg Tablet

Ipca Laboratories Ltd

₹13.72/tablet

13% costlier

Lumether 20mg/120mg Tablet

Themis Medicare Ltd

₹9.54/tablet

21% cheaper

Ecother XL Tablet

Leo Pharmaceuticals

₹12.72/tablet

5% costlier

Lumart 20 mg/120 mg Tablet

McW Healthcare

₹13.67/tablet

13% costlier

Rezatrin 20 mg/120 mg Tablet

Shreya Life Sciences Pvt Ltd

₹13/tablet

7% costlier

View all substitutes

Quick tips

Combither Tablet

You have been prescribed Combither 20mg/120mg Tablet for the treatment of acute uncomplicated malaria that is resistant to other antimalarial medications such as chloroquine.
Tips to reduce the chance of being bitten by mosquitoes:
- Wear light-coloured and covered clothing when you are outside after sunset.
- Use insect repellent creams or sprays on parts of your body not covered by clothing.
- Spray to kill any mosquitoes that may have entered rooms in spite of screening.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
It should be taken with food or drinks rich in fat such as milk.
It may cause fatigue and dizziness. Use caution while driving or doing anything that requires concentration.
If you vomit within 1 hour of taking the tablets, take another dose.
Inform your doctor if you have kidney, liver or heart disease.

Fact Box

Habit Forming

Therapeutic Class

ANTI MALARIALS

Patient concerns

Typhoid.treament feom doctor is xone injection and combither syruo My daughter has typhoid Whay should i do

Dr. Gopal Samdani

Paediatrics

Please share your few recent prescriptions and Reports of investigations done in recent past for this problem. Your Question is not very clear to me . Please ask your question more clearly and in detail and also try be more specific and descriptive.

Which medicine use for Malaria? What is eating in Malaria?

Dr. Saurav Arora

Homeopathy

The medicine depends upon symptoms and stage of disease

I have fever since last four days, I was prescribed zifi 200 and zerodol p by my doctor, but I started getting rashes, reactions, so the doctor stopped the meds, and said to have crocin only, now fourth day is over, fever comes down after having crocin then comes back again. Body ache, and headache is there, fever reaches 103, 103.8 easily every morning, have pain in my eyes also. Had zathrin 250 in the morning and at night today with crocin, my doctor suggested it on phone. What do I have? And why am I not getting better? What medication should I take?

Dr. Pushkar Mani

Physician

do malaria card test & widal

FAQs

Combither Tablet

How to take Combither 20mg/120mg Tablet?

Take Combither 20mg/120mg Tablet with food, exactly as prescribed by your doctor. This medicine is usually taken twice a day with a meal for 3 days, or as directed. On your first day of treatment, take your first dose with food, followed by your second dose 8 hours later. Then for the next 2 days, take one dose in the morning and one dose in the evening. Patients should be encouraged to resume normal eating as soon as food can be tolerated, since this improves the absorption of the medicine.

Can I take Combither 20mg/120mg Tablet while I am pregnant?

No, Combither 20mg/120mg Tablet is considered to be harmful for women in their first trimester of pregnancy. The reason being, it increases the chances of fetal loss.

Are there any specific contraindications associated with the use of Combither 20mg/120mg Tablet?

The use of Combither 20mg/120mg Tablet is considered to be harmful for patients with a known hypersensitivity to any of the active or inactive ingredients of the medicine. Caution is advised in patients with cases of severe malaria and in the first trimester of pregnancy.

What should I know about the storage and disposal of Combither 20mg/120mg Tablet?

It is advised to keep this medicine in the container it came in, tightly closed. It should be kept out of reach of children. Store it at room temperature and away from excess heat and moisture.

Related lab tests

Malarial Falciparum & Vivax Antigen

Malarial Parasite Identification

Peripheral Smear Examination

Peripheral Smear for Malaria

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Artemether+Lumefantrine. Camberley Surrey: Novartis Pharmaceuticals UK Ltd.; 1999 [revised 31 May 2017]. [Accessed 10 Apr. 2019] (online) Available from:
Artemether/lumefantrine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009. [Accessed 10 Apr. 2019] (online) Available from:

Marketer details

Name: Aristo Pharmaceuticals Pvt Ltd

Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.