Defmaze 6mg Oral Suspension belongs to a group of medicines known as corticosteroids. Its anti-inflammatory and immunosuppressive properties give it the ability to treat a wide range of conditions in children. It is also one of the primary medicines used for Duchenne muscular dystrophy in infants and children.

Many modern health problems involve inflammation. When the immune system goes into action, inflammation can get out of control and cause damage or pain. Defmaze 6mg Oral Suspension is a chemical that can stop inflammation

Uses of Defmaze 6mg Oral Suspension in children

Treatment of Cancer
Treatment of Inflammatory conditions
Treatment of Autoimmune conditions
Treatment of Duchenne muscular dystrophy(DMD)

Benefits of Defmaze 6mg Oral Suspension for your child

In Treatment of Cancer

Defmaze 6mg Oral Suspension helps in the treatment of a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It works by suppressing the immune system thereby reducing inflammation around the site of cancer. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain. Moreover, it helps to treat or prevent allergic reactions in cancer patients.

In Treatment of Inflammatory conditions

Defmaze 6mg Oral Suspension gives relief in inflammatory conditions that affect muscles and joints such as arthritis and ankylosing spondylitis. It also helps manage other inflammatory conditions such as asthma, inflammatory bowel disease, uveitis, ulcerative colitis, and allergies. It works by blocking certain chemicals that cause pain and swelling.

In Treatment of Autoimmune conditions

Defmaze 6mg Oral Suspension gives relief in autoimmune conditions like psoriasis, rheumatoid arthritis, eczema, atopic dermatitis, etc. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching, and other allergic-type reactions.

In Treatment of Duchenne muscular dystrophy(DMD)

Duchenne muscular dystrophy (DMD) is a type of muscular dystrophy, characterized by muscle weakness and atrophy due to the effect of the body’s immune system mechanisms. Defmaze 6mg Oral Suspension slows the progression of DMD. The exact mechanism by which it acts is unclear, but it is thought to help mediate the condition by suppressing the immune system. For DMD, Defmaze 6mg Oral Suspension is approved to be used in children above 5 years of age.

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Side effects of Defmaze 6mg Oral Suspension in children

Defmaze 6mg Oral Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Defmaze

Mood changes
Abdominal pain
Increased appetite
Weight gain
Back pain
Common cold
Constipation
Nausea
Nosebleeds
Fever
Stretch marks
Polyuria
Rash
Erythema (skin redness)
Central obesity
Excessive hair growth on face
Memory loss

How can I give Defmaze 6mg Oral Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Defmaze 6mg Oral Suspension may be taken with or without food, but it is better to take it at a fixed time.
Avoid Defmaze 6mg Oral Suspension with salad and vegetable diet.

How Defmaze Oral Suspension works

Defmaze 6mg Oral Suspension is a corticosteroid medicine. It acts like the body’s natural anti-inflammatory hormones called glucocorticoids. Defmaze 6mg Oral Suspension decreases the formation of chemical substances like prostaglandins, leukotrienes, and interleukins that are involved in inflammation, allergy, and cell multiplication. It also suppresses the immune system and stops the immune mechanisms from causing any self-damage to the body.

Safety advice

Kidney

SAFE IF PRESCRIBED

Defmaze 6mg Oral Suspension is safe to use in patients with kidney disease. No dose adjustment of Defmaze 6mg Oral Suspension is recommended.
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defmaze 6mg Oral Suspension to your child.

Liver

CAUTION

Defmaze 6mg Oral Suspension should be used with caution in patients with liver disease. Dose adjustment of Defmaze 6mg Oral Suspension may be needed. Please consult your doctor.

What if I forget to give Defmaze 6mg Oral Suspension to my child?

Do not panic. Unless your child’s doctor has advised a specific regime for your child, give the missed dose as soon as you remember it. Skip the missed dose if it is almost the time for the next dose. Do not give a double dose to catch up and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Defmaze 6mg Oral Suspension

₹88.0/Oral Suspension

Defcort Oral Suspension

Macleods Pharmaceuticals Pvt Ltd

₹69.85/oral suspension

21% cheaper

Cortimax Suspension

Zuventus Healthcare Ltd

₹76.75/oral suspension

13% cheaper

Dezacor Oral Suspension

Aristo Pharmaceuticals Pvt Ltd

₹85/oral suspension

3% cheaper

Enzocort Oral Suspension

Alkem Laboratories Ltd

₹100/oral suspension

14% costlier

Laza 6mg/5ml Oral Suspension

Viilbery Healthcare Pvt Ltd

₹65/oral suspension

26% cheaper

View all substitutes

Quick tips

Prefer giving Defmaze 6mg Oral Suspension with food as an empty stomach can trigger acidity and gastric reflux.
Avoid giving antacids along with Defmaze 6mg Oral Suspension. If both need to be given, leave a gap of at least 2 hours between administration of Defmaze 6mg Oral Suspension and antacids.
Do not give it more often or for longer than advised by your doctor.
Defmaze 6mg Oral Suspension can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.
Defmaze 6mg Oral Suspension helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
Do not use it more often or for longer than advised by your doctor.
Take it with food to avoid an upset stomach.
Defmaze 6mg Oral Suspension can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
Side effects such as mood changes or stomach problems can happen when you start taking Defmaze 6mg Oral Suspension. Inform your doctor if this bothers you.
Do not stop taking Defmaze 6mg Oral Suspension suddenly without talking to your doctor first as it may worsen your symptoms.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogins and derivatives

Habit Forming

Therapeutic Class

HORMONES

Action Class

Glucocorticoids

Patient concerns

Duchenne Muscular Dystrophy & Developmental delay , speech delay

Dr. Gopal Samdani

Paediatrics

Your Question is not clear to me . Please ask your question more clearly and in detail and also try be more specific and descriptive.

Babu ke muscular dystrophy genetic problam 48&50gens delite dmd Muscular dystrophy genetic problam medcian pls

Dr. Vipul Aggarwal

Orthopaedics

There are no medcines for It as far as my knowledge is concernedAnd these case are seen by PediatricianPlease let me know if there is any itber way i can help u

FAQs

In what conditions should I avoid giving Defmaze 6mg Oral Suspension to my child?

Avoid giving Defmaze 6mg Oral Suspension to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Defmaze 6mg Oral Suspension should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.

What do I need to know about Defmaze 6mg Oral Suspension and my child’s immunizations?

For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Defmaze 6mg Oral Suspension. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Defmaze 6mg Oral Suspension.

How can I store Defmaze 6mg Oral Suspension at home?

Keep the medicine in a cool dry place out of the reach of children and pets. This will help avoid any accidental intake.

My child is suffering from a seizure disorder. Is it safe to give Defmaze 6mg Oral Suspension to my child?

Ans: Prolonged intake of Defmaze 6mg Oral Suspension can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Defmaze 6mg Oral Suspension.

Is Defmaze 6mg Oral Suspension a steroid?

Yes, Defmaze 6mg Oral Suspension is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defmaze 6mg Oral Suspension increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).

What is Defmaze 6mg Oral Suspension used for?

Defmaze 6mg Oral Suspension has anti-inflammatory and immunosuppressant properties. It is used for treating conditions like allergy diseases, anaphylaxis, asthma, rheumatoid arthritis, inflammatory skin diseases and autoimmune diseases (these diseases happen when your body’s immune system attacks the body itself and causes damage). The medicine also helps transplant patients as it suppresses the immune system so that the body does not reject the organ.

How does Defmaze 6mg Oral Suspension work?

Defmaze 6mg Oral Suspension is a steroid medicine also known as glucocorticoids which occur naturally in the body. The medicine works by reducing the inflammation which helps in treating many illnesses caused due to active inflammation. Also, it stops the reactions known as autoimmune reactions which occur when your body's immune system attacks the body itself and causes damage.

Is Defmaze 6mg Oral Suspension better than Prednisone?

Clinical studies have shown that Defmaze 6mg Oral Suspension has a similar effect as that of prednisone. Moreover, Defmaze 6mg Oral Suspension is better tolerated when used in the treatment of inflammatory conditions. However, consult your doctor for the right treatment of your condition.

Is Defmaze 6mg Oral Suspension a painkiller?

No, Defmaze 6mg Oral Suspension is not a painkiller. It belongs to the class of medicines known as steroids.

Can I take Defmaze 6mg Oral Suspension with Tamsulosin?

Yes, Defmaze 6mg Oral Suspension can be taken with Tamsulosin. No harmful effects or any other interactions have been reported when they are used together.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

University of Michigan: C.S. Mott Children’s Hospital. Deflazacort. [Updated 19 Ju. 2019]. [Accessed 18 Feb. 2021] (online) Available from:
Memorial Sloan Kettering Cancer Center. Deflazacort. [Accessed 18 Feb. 2021] (online) Available from:
Mayo Clinic: Drugs and Supplements. Deflazacort (Oral Route). [Accessed 18 Feb. 2021] (online) Available from:
Emflaza (deflazacort). Frequently asked questions. [Accessed 18 Feb. 2021] (online) Available from:

Marketer details

Name: Mediganza Healthcare

Address: SCF-374, AKS Colony, Behind Bank of Maharashtra, Zirakpur Zirakpur - 140603, Punjab, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.