Depentral D 30mg/10mg Capsule SR is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort.

Depentral D 30mg/10mg Capsule SR is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

Most common side effects are stomach pain, diarrhea, headache, flatulence, dryness in mouth, and weakness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It may also cause sleepiness and dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Depentral D Capsule SR

Gastroesophageal reflux disease (Acid reflux)
Peptic ulcer disease

Benefits of Depentral D Capsule SR

In Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Depentral D 30mg/10mg Capsule SR reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

In Peptic ulcer disease

Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Depentral D 30mg/10mg Capsule SR reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.

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Side effects of Depentral D Capsule SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Depentral D

Stomach pain
Diarrhea
Headache
Flatulence
Dryness in mouth
Weakness
Flu-like symptoms

How to use Depentral D Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depentral D 30mg/10mg Capsule SR is to be taken empty stomach.

How Depentral D Capsule SR works

Depentral D 30mg/10mg Capsule SR is a combination of two medicines: Domperidone and Dexrabeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Dexrabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Depentral D 30mg/10mg Capsule SR. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Depentral D 30mg/10mg Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Depentral D 30mg/10mg Capsule SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Depentral D 30mg/10mg Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Depentral D 30mg/10mg Capsule SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Depentral D 30mg/10mg Capsule SR may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Depentral D 30mg/10mg Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Depentral D 30mg/10mg Capsule SR may be needed. Please consult your doctor.
Use of Depentral D 30mg/10mg Capsule SR is not recommended in patients with moderate and severe liver disease.

What if you forget to take Depentral D Capsule SR?

If you miss a dose of Depentral D 30mg/10mg Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Depentral D 30mg/10mg Capsule SR

₹14.0/Capsule SR

Dexpraz-DSR Capsule

AAR ESS Remedies Pvt Ltd

₹18.69/capsule sr

34% costlier

Dexa SR Capsule

Zunison Healthcare

₹40/capsule sr

186% costlier

Diorob DX 30mg/10mg Capsule SR

Divine Lifecare Pvt Ltd

₹10/capsule sr

29% cheaper

Rozydex-DSR 30mg/10mg Capsule

Zodak Healthcare

₹10.4/capsule sr

26% cheaper

Rabidex DSR Capsule

Nexure Lifesciences Pvt Ltd

₹9.8/capsule sr

30% cheaper

View all substitutes

Quick tips

You have been prescribed Depentral D 30mg/10mg Capsule SR for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

Having problem of acid reflux disease with throat infection and pain in right side of abdomen

Dr. Aanchal Maheshwari

Ayurveda

take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,,

Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen

Dr. Saurav Arora

Homeopathy

Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly,

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 12 Apr. 2019] (online) Available from:
International Breastfeeding Center. Domperidone. [Accessed 12 Apr. 2019] (online) Available from:
Rabeprazole sodium. Hatfield, Hertfordshire: Eisai Ltd.; 2008 [revised 11 Oct. 2017]. [Accessed 12 Apr. 2019] (online) Available from:

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.