Dermotrex 1% Gel is a medicine used to treat a severe form of skin disease called psoriasis when other treatments are not effective. The medicine help kills the cells in the skin which are growing too quickly. It may be also used to treat other conditions, as determined by the doctor.

Dermotrex 1% Gel may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol while taking this medicine as it may increase your risk of liver damage.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, abdominal pain, tiredness, and mouth sores. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, x-rays, and physical examinations both before and during treatment with this medicine to check for these.
Before taking it, tell your doctor if you are pregnant, have problems related to the stomach, liver, or kidney, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding as it may harm the baby.

Uses of Dermotrex Gel

Treatment of Psoriasis

Benefits of Dermotrex Gel

In Treatment of Psoriasis

Dermotrex 1% Gel belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Dermotrex 1% Gel works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Dermotrex Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dermotrex

No common side effects seen

How to use Dermotrex Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Dermotrex Gel works

Dermotrex 1% Gel is an immunosuppressant. In psoriasis, it works by slowing down the rapid growth of skin cells.

Safety advice

Alcohol

No interaction found/established

Pregnancy

UNSAFE

Dermotrex 1% Gel is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Dermotrex 1% Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

What if you forget to take Dermotrex Gel?

If you miss a dose of Dermotrex 1% Gel, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Dermotrex 1% Gel

₹441.0/Gel

Rextop 1% Gel

Systopic Laboratories Pvt Ltd

₹125/gel

72% cheaper

Folitrax LP Gel

Ipca Laboratories Ltd

₹305/gel

31% cheaper

Trexjoy Gel

Intas Pharmaceuticals Ltd

₹325/gel

26% cheaper

Fact Box

Chemical Class

Glutamic Acid Derivative

Habit Forming

Therapeutic Class

DERMA

Action Class

Antimetabolite- Methotrexate

Patient concerns

I have some rashes like patches on scalp Fungal infection

Dr. Rajesh Garg

Internal Medicine

Sent Pict. May be psoriasis

Will soriasis come because of tonsils

Dr. Atula Gupta

Dermatology

Yes . Guttate psoriasis can flare up if you have tonsillitis . But the occurrence of. Psoriasis is mostly genetic in nature

FAQs

Is Dermotrex 1% Gel effective?

Dermotrex 1% Gel is effective if used in the dose and duration advised by your doctor. Do not stop using it even if you see improvement in your condition. If you stop using Dermotrex 1% Gel too early, the symptoms may return or worsen.

How to use Dermotrex 1% Gel?

Before using Dermotrex 1% Gel, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If Dermotrex 1% Gel gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.

What precautions do I need to take while using Dermotrex 1% Gel?

Be careful not to get Dermotrex 1% Gel into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Dermotrex 1% Gel if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Dermotrex 1% Gel with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive to avoid any harm to the baby. Pregnant and breastfeeding mothers should use Dermotrex 1% Gel only if prescribed by the doctor.

What should I do if I forget to use Dermotrex 1% Gel?

If you forget to use Dermotrex 1% Gel, do not worry and continue using Dermotrex 1% Gel as soon as you remember. Do not double the dose to make up for the missed dose. However, if you are not sure and have any other doubts, please consult your doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
Central Drugs Standard Control Organisation. Methotrexate. [Accessed 11 Jul. 2023]. (online) Available from:
American Academy of Dermatology Association. Psoriasis Treatment: Methotrexate. [Accessed 11 Jul. 2023]. (online) Available from:
Eskicirak B, Zemheri E, Cerkezoglu A. The treatment of psoriasis vulgaris: 1% topical methotrexate gel. Int J Dermatol. 2006 Aug;45(8):965-9. [Accessed 11 Jul. 2023]. (online) Available from:

Marketer details

Name: East West Pharma

Address: No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.