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Dibizide-M Tablet

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Product introduction

Dibizide-M Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Dibizide-M Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Dibizide-M Tablet is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.


Uses of Dibizide-M Tablet


Side effects of Dibizide-M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dibizide-M

  • Headache
  • Diarrhea
  • Hypoglycemia (low blood glucose level)

How to use Dibizide-M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dibizide-M Tablet is to be taken with food.

How Dibizide-M Tablet works

Glipizide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Dibizide-M Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Dibizide-M Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Dibizide-M Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Dibizide-M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Dibizide-M Tablet may be needed. Please consult your doctor.
Use of Dibizide-M Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Dibizide-M Tablet should be used with caution in patients with liver disease. Dose adjustment of Dibizide-M Tablet may be needed. Please consult your doctor.
Dibizide-M Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you forget to take Dibizide-M Tablet?

If you miss a dose of Dibizide-M Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Dibizide-M Tablet
₹1.45/Tablet
₹1.85/tablet
28% costlier
Glimet DS Tablet
Franco-Indian Pharmaceuticals Pvt Ltd
₹1.64/tablet
13% costlier
Glyson-MF Tablet
Unison Pharmaceuticals Pvt Ltd
₹1.81/tablet
25% costlier
Metaglez Forte Tablet
Aristo Pharmaceuticals Pvt Ltd
₹1.94/tablet
34% costlier
Glucotrol MF 5 mg/500 mg Tablet
Jenburkt Pharmaceuticals Ltd
₹1.64/tablet
13% costlier

Quick tips

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Dibizide-M Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Dibizide-M Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

Patient concerns

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Can i use dibizide m along with insulin
Dr. Ashwin Porwal
Internal Medicine
you can use them together but not with doctor's prescription
Having itching in body & small small piti
Dr. Pushkar Mani
Physician
dazit m tablet twice daily for5 days
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User feedback


FAQs

Q. What is Dibizide-M Tablet?

Dibizide-M Tablet is a combination of two medicines: Glipizide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glipizide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Dibizide-M Tablet?

The use of Dibizide-M Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to Vitamin B12 deficiency.

Q. Can the use of Dibizide-M Tablet cause hypoglycemia?

Yes, the use of Dibizide-M Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you.

Q. Can the use of Dibizide-M Tablet cause lactic acidosis?

Yes, the use of Dibizide-M Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Dibizide-M Tablet and immediately consult your doctor.

Q. Can the use of Dibizide-M Tablet lead to Vitamin B12 deficiency?

Yes, the use of Dibizide-M Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in the hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Dibizide-M Tablet should not to be taken?

The use of Dibizide-M Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Dibizide-M Tablet?

No, it is not safe to take Dibizide-M Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Dibizide-M Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Dibizide-M Tablet?

Dibizide-M Tablet is a combination of two medicines: Glipizide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glipizide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Dibizide-M Tablet?

The use of Dibizide-M Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to Vitamin B12 deficiency.

Q. Can the use of Dibizide-M Tablet cause hypoglycemia?

Yes, the use of Dibizide-M Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you.

Q. Can the use of Dibizide-M Tablet cause lactic acidosis?

Yes, the use of Dibizide-M Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Dibizide-M Tablet and immediately consult your doctor.

Q. Can the use of Dibizide-M Tablet lead to Vitamin B12 deficiency?

Yes, the use of Dibizide-M Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in the hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Dibizide-M Tablet should not to be taken?

The use of Dibizide-M Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Dibizide-M Tablet?

No, it is not safe to take Dibizide-M Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Dibizide-M Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Glipizide+metformin HCl. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 29 Jan. 2019] (online) Available from:External Link
  2. Glipizide and Metformin Hydrochloride. Ahmedabad, India: Cadila Healthcare Ltd; 2016. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Medscape. Glipizide/Metformin. [Accessed 24 Sept. 2021] (online) Available from:External Link
  4. American Diabetes Association. 14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes-2021. Diabetes Care. 2021;44(Suppl 1):S200-S210. [Accessed 20 Sept. 2021] (online) Available from:External Link
  5. Glipizide and metformin [Drug Label]. Princeton, NJ: Bristol-Myers Squibb Company: 2008. [Accessed 21 Aug. 2024] (online) Available from: External Link

Marketer details

Name: Micro Labs Ltd
Address: 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Dibizide-M Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP
14.5
Inclusive of all taxes
10.0 tablets in 1 strip
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