Difiram 250 Tablet is a medicine used in the treatment of alcohol addiction. It works by producing interaction with alcohol and thereby causing unpleasant effects like nausea, flushing of the face, headaches. Thus, it discourages the patient from taking alcohol while on this medication.

Difiram 250 Tablet is used in the treatment of people with drinking problems. People who drink while taking Difiram 250 Tablet, the patient experiences unpleasant physical features

Uses of Difiram Tablet

Treatment of Alcohol addiction

Benefits of Difiram Tablet

In Treatment of Alcohol addiction

Difiram 250 Tablet is a medicine used, along with social support and counseling, to help people recover from alcohol addiction and to avoid having the urge to drink alcohol again. It causes sudden, undesirable effects when mixed with alcohol to help you refrain from alcohol, even if you are dependent on alcohol. It causes effects such as flushing of the face, headache, nausea, blurred vision, mental confusion etc., when even small amounts of alcohol are consumed.

Difiram 250 Tablet starts working from the very first dose and is a very safe and effective way of treating alcohol addiction. Avoid taking foods containing alcohol like mouthwash, cough medicines, perfumes or deodorants, and even hair dyes as even small amounts of alcohol can trigger these unpleasant effects.

Side effects of Difiram Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Difiram

Headache
Fatigue
Drowsiness
Metallic taste

How to use Difiram Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Difiram 250 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Difiram 250 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Difiram 250 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Difiram 250 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Difiram 250 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Difiram 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Difiram 250 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Difiram 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Difiram 250 Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Difiram 250 Tablet

₹2.9/Tablet

Disulfiram 250mg Tablet

Intas Pharmaceuticals Ltd

₹2.9/tablet

same price

Deadict 250mg Tablet

Psychotropics India Ltd

₹4.4/tablet

52% costlier

Firam 250mg Tablet

Tripada Healthcare Pvt Ltd

₹1.46/tablet

50% cheaper

Soberol 250 Tablet

Consern Pharma Limited

₹2.73/tablet

6% cheaper

Tyfusin 250mg Tablet

KC Laboratories

₹5.88/tablet

103% costlier

View all substitutes

Quick tips

Difiram 250 Tablet is used together with behavior modification, psychotherapy, and counseling support to help you stop drinking.
It works best for patients who can achieve initial abstinence of at least 12 hours, are committed to maintaining abstinence, and agree to take the medication.
While taking this medication, avoid alcohol in all forms including beer, wine, aftershave lotions, mouthwash, vinegar, certain desserts, colognes, and liquid medications.
When you first start taking it, you may feel dizzy, confused, tired, and weak. Don't drive or do anything that requires mental focus until you know how it affects you.
You may notice an aftertaste of either garlic or metal when you start taking Difiram 250 Tablet. Inform your doctor if this does not go away.
Inform your doctor if you have a history of heart disease, liver or kidney disease, psychiatric problems, diabetes, or if you're allergic to latex rubber or pesticides.
Do not take it if you are pregnant, planning a pregnancy, or breastfeeding.

Fact Box

Chemical Class

Carbamate Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Alcohol deaddiction

Patient concerns

I have a problem with alcohol addiction

Dr. Aanchal Maheshwari

Ayurveda

Take gaharwar deaddiction capsule 1 capsule dailyDo ,yoga and meditation

Is kripa rehabilitation center Bangalore good for de-addiction of alcohol?

Dr. Jyoti Kapoor Madan

Psychiatry

I am not sure!

FAQs

Q. Is Difiram 250 Tablet safe/dangerous?

Yes, Difiram 250 Tablet is safe if used at prescribed doses for the prescribed duration in a hospital or specialized clinic as advised by your special doctor

Q. Is Difiram 250 Tablet over-the-counter medicine?

No, Difiram 250 Tablet is not an over-the-counter medicine. Difiram 250 Tablet treatment for alcohol withdrawal should be initiated only in a hospital or specialized clinic and by experienced doctors only. Patients should follow advice of the doctor regarding its use

Q. Is Difiram 250 Tablet addictive?

No, Difiram 250 Tablet is not addictive. It is used to treat alcohol addiction and chronic alcoholism

Q. Does Difiram 250 Tablet work?

Yes, Difiram 250 Tablet works. Difiram 250 Tablet is an aldehyde dehydrogenase inhibitor. It works by blocking the processing of alcohol in the body causing unpleasant feeling leading to alcohol withdrawal

Q. Does Difiram 250 Tablet work for everyone?

Difiram 250 Tablet works for chronic alcoholics who are cooperative and willing to give up alcoholism. Patients should follow advice of the doctor regarding its use

Q. Does Difiram 250 Tablet stops cravings?

Difiram 250 Tablet blocks the processing of alcohol in the body causing unpleasant feeling due to these unpleasant episodes, alcoholics abstain from alcohol Therefore, patients may avoid consuming alcohol to avoid unpleasant reactions upon consuming alcohol even days after stopping Difiram 250 Tablet. It may not have any direct effects on cravings

Q. Does Difiram 250 Tablet work immediately?

Yes, Difiram 250 Tablet works on alcohol withdrawal as soon as you start the treatment

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Disulfiram. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 195-97.
Schuckit MA. Ethanol and Methanol. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 643-44.
Masters SB. The Alcohols. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 395.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 420-21.
Schuckit MA. Ethanol and Methanol. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 29 Jan. 2019] (online) Available from:

Marketer details

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Address: arvinda ghosh marg, ramdaspeth, akola, maharashtra 444001

Country of origin: India

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