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Last updated
25 Nov 2023 | 11:59 PM (IST)

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Domi UP Oral Spray

Prescription Required

Product introduction

Domi UP Oral Spray is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.

Domi UP Oral Spray is used to prevent and treat nausea and vomiting.

Uses of Domi UP Oral Solution

Benefits of Domi UP Oral Solution

In Treatment of Nausea

Chemotherapy, radiotherapy, major surgeries, and abdominal infection put your child at risk of developing severe nausea and vomiting. It happens due to the release of a chemical called serotonin. Domi UP Oral Spray acts by blocking the effect of this chemical and prevents nausea and vomiting. It also helps your child to recover more comfortably from these treatments. Stick to the prescribed dose, time, and way, and do not increase or decrease the dose by yourself without consulting your child’s doctor as it may result in side effects.

Side effects of Domi UP Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Domi UP

  • Headache
  • Constipation
  • Diarrhea
  • Fatigue

How to use Domi UP Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Domi UP Oral Spray may be taken with or without food, but it is better to take it at a fixed time.

How Domi UP Oral Solution works

During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Domi UP Oral Spray just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.

Safety advice

Alcohol
SAFE
Consuming alcohol with Domi UP Oral Spray does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Domi UP Oral Spray is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Domi UP Oral Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Domi UP Oral Spray does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Domi UP Oral Spray is safe to use in patients with kidney disease. No dose adjustment of Domi UP Oral Spray is recommended.
Liver
CAUTION
Domi UP Oral Spray should be used with caution in patients with liver disease. Dose adjustment of Domi UP Oral Spray may be needed. Please consult your doctor.

What if you forget to take Domi UP Oral Solution?

Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Domi UP Oral Spray
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Quick tips

  • Domi UP Oral Spray effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
  • It is fast-acting and starts working within 30 minutes.
  • Practice self-care measures:
    1. Give plenty of fluids to your child to avoid dehydration
    2. Avoid giving fried and spicy food or heavy meals to your child. 
    3. Ensure that your child eats slowly and in small proportions.

Fact Box

Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin antagonists (5-HT3 antagonists)

Patient concerns

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Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.
Vomiting, nausea neck pain backside
Dr. Vijay Verma
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Neck pain may be due to nausea NAD vomiting Visit physician for the same
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User feedback


FAQs

Q. What is Domi UP Oral Spray used for?

Domi UP Oral Spray is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, your child’s doctor may ask you to give Domi UP Oral Spray to your child to prevent vomiting post-procedure. Apart from this, Domi UP Oral Spray is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Domi UP Oral Spray to your child for a few days. Stick to the dose for best results.

Q. What if my child takes too much Domi UP Oral Spray?

Domi UP Oral Spray is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Domi UP Oral Spray can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.

Q. How should Domi UP Oral Spray be stored?

Domi UP Oral Spray should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.

Q. What all medicines should my child avoid while taking Domi UP Oral Spray?

Usually, it is advised not to give Domi UP Oral Spray along with antidepressant medicines, apomorphine, anti-migraine medicines, painkillers, heart medicines, and antibiotics like linezolid. But, it is ideal to speak to your child’s doctor before coming to any conclusion. So, narrate your child’s complete medical history to your child’s doctor and follow their advice strictly.

Q. In what conditions do I need to call my child’s doctor right away?

Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.

Q. My child is having a migraine and is on medication. Can I give Domi UP Oral Spray along with it?

Avoid combining Domi UP Oral Spray with such medicines because concomitant use of Domi UP Oral Spray with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:External Link
  2. Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:External Link

Marketer details

Name: Lincoln Pharmaceuticals Ltd
Address: LINCOLN HOUSE, B/h. Satyam Complex, Science City Road, Sola, Ahmedabad – 380 062., Gujarat, India,
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Domi UP Oral Spray. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP
37.4
Inclusive of all taxes
30.0 ml in 1 bottle
Add to cart
Cash on delivery available

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