Evelis Tablet is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.

Evelis Tablet is used to prevent the body rejecting the organ that is transplanted and also to prevent cancer post organ transplant

Uses of Evelis Tablet

Benefits of Evelis Tablet

In Prevention of organ rejection in transplant patients

Evelis Tablet is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

In Treatment of Breast cancer

Evelis Tablet is used to treat breast cancer in postmenopausal women when other medicines have failed to show significant improvement. It helps to stop cancer growth and further spread and relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. Take is as advised to get maximum relief.

In Treatment of Pancreatic cancer

Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Evelis Tablet helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.

In Treatment of Lung cancer

Evelis Tablet reduces the blood supply to the cancer cells and stops its growth. But, as it reduces the immunity, avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to. Take a healthy diet and keep taking the medicine as prescribed to get the full benefits.

In Treatment of Kidney cancer

Evelis Tablet is used to treat kidney cancer when other medicines have failed to work. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover. Take it as prescribed to get the maximum benefit.

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Side effects of Evelis Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Evelis

Weakness
Sinus inflammation
Infection
Fever
Cough
Fatigue
Stomatitis (Inflammation of the mouth)
Otitis media (infection of ear)
Diarrhea
Upper respiratory tract infection

How to use Evelis Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Evelis Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Evelis Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Evelis Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Evelis Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Evelis Tablet may cause side effects which could affect your ability to drive.
As fatigue is a common side effect with Evelis Tablet and this may affect your ability to drive

Kidney

SAFE IF PRESCRIBED

Evelis Tablet is safe to use in patients with kidney disease. No dose adjustment of Evelis Tablet is recommended.

Liver

CAUTION

Evelis Tablet should be used with caution in patients with liver disease. Dose adjustment of Evelis Tablet may be needed. Please consult your doctor.
Use of Evelis Tablet is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Evelis Tablet

₹1918.0/Tablet

Evermil 10 Tablet

Glenmark Pharmaceuticals Ltd

₹745/tablet

61% cheaper

Afinitor 10mg Tablet

Novartis India Ltd

₹1988.24/tablet

4% costlier

Evertor 10mg Tablet

Biocon

₹1469.09/tablet

23% cheaper

Rolimus 10 Tablet

Cipla Ltd

₹990/tablet

48% cheaper

Volantis 10mg Tablet

Dr Reddy's Laboratories Ltd

₹983.75/tablet

49% cheaper

View all substitutes

Quick tips

Evelis Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection.
Evelis Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Evelis Tablet increases your risk of getting an infection.
While you are taking Evelis Tablet do not take any vaccinations without talking to your doctor first.
If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Evelis Tablet.
Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Evelis Tablet.

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- mTOR inhibitors

Patient concerns

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

If any symtom of brest cancer if have whats the cure

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

First is confirmation of breast cancerChance of cure depends on stage of cancer

FAQs

Is any monitoring required while taking Evelis Tablet?

Regular monitoring is required while you are on Evelis Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Evelis Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.

What should I avoid while taking Evelis Tablet?

You should avoid grapefruit or grapefruit juice while taking Evelis Tablet. This is because taking them together may increase the levels of Evelis Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.

What is the most important information I need to know about Evelis Tablet?

Evelis Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.

Is Evelis Tablet a chemotherapy?

Evelis Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.

How is Evelis Tablet administered?

Usually, Evelis Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Evelis Tablet should be swallowed whole with water and should not be crushed or chewed.

How long can you take Evelis Tablet?

There is no definite duration of treatment with Evelis Tablet. Evelis Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.

How will I know that Evelis Tablet is shrinking my brain tumor?

The effect of Evelis Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.

Is Evelis Tablet cytotoxic?

Yes, Evelis Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).

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Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

Complete Blood Count

Related ayurvedic ingredients

Fish Oil

Olive oil

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1013.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 526.
Everolimus. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Apr. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
Everolimus. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2011 [revised 12 Jul 2018]. [Accessed 22 Jan. 2019] (online) Available from:

Marketer details

Name: Axiommax Oncology Pvt Ltd

Address: A/303, Atrium -1, Andheri - Kurla Road, Mumbai – 400 059 India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.