Istapin M 500mg/20mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may also reduce your chances of having a heart attack or stroke.

Istapin M 500mg/20mg Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It provides better control of blood sugar when single therapy is not effective and reduces both fasting and postmeal sugar levels. It should be used along with a proper diet and exercise for maximum effect. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level) as a side effect.

Uses of Istapin M Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Istapin M Tablet

In Treatment of Type 2 diabetes mellitus

Istapin M 500mg/20mg Tablet is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.

Side effects of Istapin M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Istapin M

Hypoglycemia (low blood glucose level)
Nausea
Vomiting
Diarrhea
Headache
Bloating
Flatulence

How to use Istapin M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istapin M 500mg/20mg Tablet is to be taken with food.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Istapin M 500mg/20mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Istapin M 500mg/20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Istapin M 500mg/20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Istapin M 500mg/20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Istapin M 500mg/20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Istapin M 500mg/20mg Tablet may be needed. Please consult your doctor.
Use of Istapin M 500mg/20mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

UNSAFE

Istapin M 500mg/20mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Istapin M Tablet?

If you miss a dose of Istapin M 500mg/20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Istapin M 500mg/20mg Tablet

₹11.7/Tablet

Totaglipt M Tablet

Mankind Pharma Ltd

₹9.9/tablet

15% cheaper

J-Ring M Tablet

Indoco Remedies Ltd

₹14.75/tablet

26% costlier

Eliptin M 500mg/20mg Tablet

HBC Lifesciences Pvt Ltd

₹20.1/tablet

72% costlier

Tenliptin M 500mg/20mg Tablet

Carise Pharmaceuticals Pvt Ltd

₹11.1/tablet

5% cheaper

Ten M 20mg/500mg Tablet

Centaur Pharmaceuticals Pvt Ltd

₹11.7/tablet

same price

View all substitutes

Quick tips

Istapin M Tablet

You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
Take it in addition to regular exercise and a healthy diet to lower levels of blood sugar.
Take it with food to lower your chance of having an upset stomach.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Istapin M 500mg/20mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

Istapin M Tablet

Q. Is it safe to use Istapin M 500mg/20mg Tablet?

Yes, it is safe to use Istapin M 500mg/20mg Tablet if you take it for the prescribed duration and according to the dosage advised by the doctor. However, despite taking the prescribed dosage you might experience common side effects like nausea, diarrhea, vomiting, stomach upset, headache, nasal congestion, sore throat, respiratory tract infection and hypoglycemia (low blood sugar level). Hypoglycemia is relatively common in patients who are taking Istapin M 500mg/20mg Tablet in combination with insulin or Sulfonylurea. Inform your doctor if you experience any persistent problem while taking this medicine.

Q. Can the use of Istapin M 500mg/20mg Tablet lead to hypoglycemia?

The use of Istapin M 500mg/20mg Tablet does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.

Q. Can the use of Istapin M 500mg/20mg Tablet cause nausea and vomiting?

Yes, the use of Istapin M 500mg/20mg Tablet can cause nausea and vomiting. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.

Q. Are there any specific contraindications associated with the use of Istapin M 500mg/20mg Tablet?

The use of Istapin M 500mg/20mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Can the use of Istapin M 500mg/20mg Tablet cause lactic acidosis?

Yes, the use of Istapin M 500mg/20mg Tablet can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Istapin M 500mg/20mg Tablet and immediately consult your doctor.

Q. Can the use of Istapin M 500mg/20mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Istapin M 500mg/20mg Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. Deficiency of B12 may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.

Q. What is the storage condition for the Istapin M 500mg/20mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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References

Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:
Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95. [Accessed 08 Apr. 2019] (online) Available from:
Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:
Teneligliptin and Metformin hydrochloride [Product Monograph] Mumbai, Maharashtra: Panacea Biotec Limited; 2019. [Accessed 20 Oct. 2021] (online) Available from:
Teneligliptin and Metformin hydrochloride [Product information] Pune, India: Centaur Pharma Ltd.; 2018. [Accessed 20 Oct. 2021] (online) Available from:
Teneligliptin and Metformin hydrochloride [Packaging information] Pune, India: Centaur Pharma Ltd. [Accessed 20 Oct. 2021] (online) Available from:

Marketer details

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Country of origin: India

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