Macabi 50mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Macabi 50mg Tablet is used in treating prostate cancer that require certain male body chemicals to grow

Uses of Macabi Tablet

Prostate cancer

Benefits of Macabi Tablet

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Macabi 50mg Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Macabi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macabi

Anemia (low number of red blood cells)
Rash
Abdominal pain
Breast enlargement in male
Breast tenderness
Constipation
Decreased appetite
Decreased libido
Depression
Dizziness
Indigestion
Flatulence
Hot flashes
Increased liver enzymes
Nausea
Sleepiness
Weakness
Weight gain

How to use Macabi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macabi 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Macabi 50mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Macabi 50mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Macabi 50mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Macabi 50mg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Macabi 50mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Macabi 50mg Tablet is recommended.

Liver

CAUTION

Macabi 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Macabi 50mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable while you are taking this medicine.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Macabi 50mg Tablet

₹40.0/Tablet

Calutide 50 Tablet

Cipla Ltd

₹52.26/tablet

31% costlier

Caluran 50 CP Tablet

Sun Pharmaceutical Industries Ltd

₹18.6/tablet

53% cheaper

Tabi Tablet

Dr Reddy's Laboratories Ltd

₹43.04/tablet

8% costlier

Caluran 50 Tablet

Sun Pharmaceutical Industries Ltd

₹29.5/tablet

26% cheaper

Utamide Tablet

Intas Pharmaceuticals Ltd

₹41.26/tablet

3% costlier

View all substitutes

Quick tips

You have been prescribed Macabi 50mg Tablet for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Macabi 50mg Tablet.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.

Fact Box

Chemical Class

Trifluoromethylbenzenes Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Androgen receptor antagonist

Patient concerns

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

May not be prostate cancer, it is only begnin enlargement of prostate.

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Not a symptom of prostate cancer

FAQs

Can Macabi 50mg Tablet cause infertility?

There is limited data to support that Macabi 50mg Tablet causes infertility. Macabi 50mg Tablet has been shown to affect fertility in animals and therefore it is assumed that it may cause fertility on humans. Some studies have shown that it affects spermatogenesis (origin and development of the sperm cells).

What should I avoid while taking Macabi 50mg Tablet?

Skin sensitivity has been observed in some patients while taking Macabi 50mg Tablet. Therefore, you should avoid direct sun exposure, sunlamps, and tanning beds. It is advised to use a sunscreen during treatment with Macabi 50mg Tablet.

Is Macabi 50mg Tablet a form of chemotherapy?

No, Macabi 50mg Tablet is not a form of chemotherapy medicine, it is anti-androgen medicine. Androgens such as testosterone are natural male sex hormones. Macabi 50mg Tablet works by blocking the effect of androgens (testosterone) in order to stop the growth and spread of cancer cells.

Does Macabi 50mg Tablet cause hair loss?

Yes, Macabi 50mg Tablet may cause hair loss as it is a common side effect. However, this does not affect everyone. Consult your doctor, if hair loss is worrying you.

What is Macabi 50mg Tablet prescribed for?

Macabi 50mg Tablet is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (prostate cancer that has spread to other parts of the body). Other than that, Macabi 50mg Tablet has been effective in treating hirsutism in patients with polycystic ovarian disease, though this is not an approved use.

When should I take Macabi 50mg Tablet?

Macabi 50mg Tablet should be taken at the same time every day either in the morning or in the evening. Take it exactly as directed by your doctor.

Can Macabi 50mg Tablet cause diarrhea?

Yes, Macabi 50mg Tablet can cause diarrhea though it is rare. Generally, constipation is more common with this medicine. Consult your doctor if it worries you.

How long do I need to take Macabi 50mg Tablet?

Macabi 50mg Tablet tablets should be taken continuously for a minimum of 2 years or until the disease persists. Do not stop taking it without consulting your doctor.

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Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

Related ayurvedic ingredients

Garlic

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 724.
Bicalutamide. Sellersville, PA: TEVA Pharmaceutical; 1995 [revised Jun. 2009]. [Accessed 26 Mar. 2019] (online) Available from:
Bicalutamide. Capability Green: AstraZeneca UK; 2000 [revised 08 Feb. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Miracalus Pharma Pvt Ltd

Address: 213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.