Megalin 500mcg/75mg Tablet is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heal damaged nerve cells.

Megalin 500mcg/75mg Tablet is a combination of two medicines: Megalin 500mcg/75mg Tablet1 and Megalin 500mcg/75mg Tablet2.

Uses of Megalin Tablet

Treatment of Neuropathic pain

Benefits of Megalin Tablet

In Treatment of Neuropathic pain

Megalin 500mcg/75mg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Pregabalin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction. Taking Megalin 500mcg/75mg Tablet regularly will improve your physical and social functioning and overall quality of life.

Side effects of Megalin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megalin

Dizziness
Sleepiness
Tiredness
Uncoordinated body movements

How to use Megalin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megalin 500mcg/75mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

UNSAFE

Megalin 500mcg/75mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Megalin 500mcg/75mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Megalin 500mcg/75mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Megalin 500mcg/75mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Megalin 500mcg/75mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Megalin 500mcg/75mg Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Megalin 500mcg/75mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Megalin 500mcg/75mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Megalin Tablet?

If you miss a dose of Megalin 500mcg/75mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Megalin 500mcg/75mg Tablet

₹10.8/Tablet

Gabawin 50 M Tablet

Icon Life Sciences

₹10.35/tablet

5% costlier

Axinerve Tablet

Avis Lifecare Pvt Ltd

₹8.2/tablet

17% cheaper

Peblin M 500mcg/75mg Tablet

Mova Pharmaceutical Pvt Ltd

₹15.17/tablet

53% costlier

Gabafit M 500mcg/75mg Tablet

Glenmark Pharmaceuticals Ltd

₹8.11/tablet

18% cheaper

Nervlin-M 500mcg/75mg Tablet

Zodley Pharmaceuticals Pvt Ltd

₹9.8/tablet

1% cheaper

View all substitutes

Quick tips

Megalin Tablet

You have been prescribed Megalin 500mcg/75mg Tablet for treating and preventing nerve pain.
Its side effects are usually mild and temporary.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid consuming alcohol when taking Megalin 500mcg/75mg Tablet, as it may cause excessive sleepiness.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

Most of the times when I get excited or have orgasm I feel pain in my testis and around it .

Dr. Pranay Gandhi

Sexology

hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd

Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.

Dr. Vikas Sharma

Neurology

dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro

I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest

Dr. Pranay Gandhi

Sexology

it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od

FAQs

Megalin Tablet

Q. What is Megalin 500mcg/75mg Tablet?

Megalin 500mcg/75mg Tablet is a combination of two medicines: Pregabalin and Methylcobalamin. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.

Q. Can I stop taking Megalin 500mcg/75mg Tablet when my pain is relieved?

No, you should not stop taking Megalin 500mcg/75mg Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Megalin 500mcg/75mg Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Megalin 500mcg/75mg Tablet before you stop the medication completely.

Q. How to manage weight gain associated with the use of Megalin 500mcg/75mg Tablet?

Megalin 500mcg/75mg Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

Q. Can the use of Megalin 500mcg/75mg Tablet cause sleepiness or drowsiness?

Yes, Megalin 500mcg/75mg Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Q. Are there any serious side effects associated with the use of Megalin 500mcg/75mg Tablet?

Serious side effects caused because of the use of Megalin 500mcg/75mg Tablet are uncommon and rare. However, it may cause serious side effects like allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Megalin 500mcg/75mg Tablet and contact your doctor if you have any signs of these serious side effects. Signs of an allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck. Allergic reactions can also lead to trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts or feelings, or if you have suicidal thoughts.

Q. How long will the Megalin 500mcg/75mg Tablet take to act?

An initial benefit with Megalin 500mcg/75mg Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months or more (in some patients) to see the full benefits.

Q. What if I forget to take Megalin 500mcg/75mg Tablet?

If you forget to take the scheduled dose of Megalin 500mcg/75mg Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Q. Will a higher than the recommended dose of Megalin 500mcg/75mg Tablet be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. Can I drink alcohol while taking Megalin 500mcg/75mg Tablet?

No, do not drink alcohol while taking Megalin 500mcg/75mg Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Megalin 500mcg/75mg Tablet.

Q. How often should I see the doctor ?

You may need to see your doctor regularly if you have started to take Megalin 500mcg/75mg Tablet. However, you must consult your doctor if the advised dosage of Megalin 500mcg/75mg Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.

Q. Are there any special instructions regarding storage and disposal of this medicine?

Keep your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

MedlinePlus. Vitamin B12. [Accessed 22 Apr. 2019] (online) Available from:
Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
PubChem. Methylcobalamin hydrate. [Accessed 22 Apr. 2019] (online) Available from:
Pregablin. New York, New York: Pfizer; 2004 [revised Jun 2011]. [Accessed 22 Apr. 2019] (online) Available from:

Marketer details

Name: Lloyd Healthcare Pvt Ltd

Address: 702, Balaji Business Park, Andheri Kurla Road, Marol Naka, Andheri East, Gamdevi, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.