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Merex 1000mg Injection

Prescription Required

Product introduction

Merex 1000mg Injection is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It may be used with other medicines as part of combination therapy.

Merex 1000mg Injection may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol while taking this medicine as it may increase your risk of liver damage.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, abdominal pain, tiredness, and mouth sores. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, x-rays, and physical examinations both before and during treatment with this medicine to check for these.
Before taking it, tell your doctor if you are pregnant, have problems related to the stomach, liver, or kidney, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding as it may harm the baby.

Benefits of Merex Injection

In Cancer

Merex 1000mg Injection belongs to a group of medicines called antimetabolites and is referred to as a cytotoxic. It works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Treatment of Rheumatoid arthritis

Merex 1000mg Injection belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body's immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective.

Side effects of Merex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Merex

  • Abdominal pain
  • Indigestion
  • Loss of appetite
  • Nausea
  • Vomiting
  • Tiredness
  • Mouth sore
  • Decreased white blood cell count

How to use Merex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Merex Injection works

Merex 1000mg Injection is an anti-cancer medication. It works by blocking an enzyme (dihydrofolate reductase) involved in DNA synthesis in cancer cells. This slows the growth of cancer cells and eventually kills them.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Merex 1000mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Merex 1000mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Merex 1000mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Merex 1000mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Merex 1000mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Merex 1000mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Merex 1000mg Injection should be used with caution in patients with liver disease. Dose adjustment of Merex 1000mg Injection may be needed. Please consult your doctor.
Use of Merex 1000mg Injection is not recommended in patients with severe liver disease.

What if you forget to take Merex Injection?

If you miss a dose of Merex 1000mg Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Merex 1000mg Injection
₹1093.0/Injection
Methocel 1000mg Injection
Celon Laboratories Ltd
₹904.76/injection
17% cheaper
Biotrexate 1000mg Injection
Biochem Pharmaceutical Industries
₹1026/injection
6% cheaper
B Trax 1000mg Injection
Health Biotech Limited
₹790/injection
28% cheaper
Trexova 1g Injection
Neova Biogene Private Limited
₹2018/injection
85% costlier
Metho ML 1000mg Injection
Metta Life Sciences Private Limited
₹1800/injection
65% costlier

Quick tips

  • Merex 1000mg Injection helps treat various types of cancer such as blood cancer, bone cancer, non-Hodgkin lymphoma (NHL), breast cancer, lung cancer, head and neck cancer, cervical cancer, ovarian cancer and testicular cancer.
  • Take it once a week, on the same day every week.
  • Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.
  • Drink plenty of liquids to stay hydrated while taking this  medication.
  • It may take 6 to 8 weeks for Merex 1000mg Injection to work. Keep taking the medication as prescribed.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
  • Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood.

Fact Box

Chemical Class
Glutamic Acid Derivative
Habit Forming
No
Therapeutic Class
abcde
Action Class
Antimetabolite- Methotrexate

Patient concerns

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I have joint pain in my rt wrist since 6 yrs. What are the possible reasons?
Dr. Trilok Kumar Jha
Orthopaedics
It may be Tenosynovitis, or Rheumatoid arthritis or any other type of arthritis
What is gatheya. What is it solution
Dr. Akshat Goel
Orthopaedics
It is supposed to be Rheumatoid Arthritis
arrow

FAQs

Q. Can Merex 1000mg Injection cause mouth ulcers?

Yes, Merex 1000mg Injection can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Q. Why do I have to take folic acid with Merex 1000mg Injection?

Merex 1000mg Injection decreases the folic acid levels in the body by flushing it out of the body. Folic acid is an essential vitamin required to make new cells in the body. By taking folic acid some of the common side effects of Merex 1000mg Injection like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems can be reduced.

Q. Why do I need to take regular blood tests while taking Merex 1000mg Injection?

Regular blood tests will help your doctor to check your response to Merex 1000mg Injection and monitor your side effects. You will need to routinely check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also advise additional tests depending on the previous test results.

Q. Can Merex 1000mg Injection use make me more prone to infections?

Merex 1000mg Injection may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports of serious lung infections with Merex 1000mg Injection use. If you have an active infection, Merex 1000mg Injection should be used with extreme caution.

Q. Can Merex 1000mg Injection affect fertility?

Yes, it may affect fertility in both males and females. There may be a decrease in sperm count in males and menstrual disturbances in females. Do not worry, these effects are reversible and disappear once the therapy is discontinued. However, if you have more concerns, consult your doctor.

Q. What to do if I am planning to become pregnant and my husband is taking Merex 1000mg Injection?

You should avoid pregnancy if your husband is taking Merex 1000mg Injection. Also, avoid pregnancy for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Methotrexate. Camberley, Surrey: Sandoz Limited; 2005 [revised 23 Mar. 2018]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  4. Methotrexate. Lake Forest, Illinois: Hospira, Inc.; 2011. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Methotrexate [Product Information]. Taj Pharma. [Accessed 04 Aug. 2023]. (online) Available from: External Link
  6. Methotrexate [New Zealand Data Sheet]. Auckland, New Zealand: Novartis New Zealand Ltd; 2023. [Accessed 04 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Merex 1000mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP
1093
Inclusive of all taxes
10.0 ml in 1 vial
Add to cart
Cash on delivery available

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