Midarine 100mg Injection belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care.

Midarine 100mg Injection are used to relax the muscles to ease the insertion of a tube into the windpipe, to help with assisted breathing and also to ensure muscle relaxation during surgery

Uses of Midarine Injection

Skeletal muscle relaxation during surgery

Benefits of Midarine Injection

In Skeletal muscle relaxation during surgery

Midarine 100mg Injection is used to relax muscles during anesthesia and surgical procedures. It works by blocking chemical messengers in the brain that are responsible for rigidity, inflammation, or swelling. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Midarine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Midarine

Stomach pressure
Excessive salivation
Muscle twitching
Postoperative muscle pain
Increased intraocular pressure
Slow heart rate
Increased heart rate
Flushing of skin
High blood pressure
Hypotension (low blood pressure)
Rash
Increased potassium level in blood

How to use Midarine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Midarine 100mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Midarine 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Midarine 100mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

NOT RELEVANT

Not relevant, as Midarine 100mg Injection is intended for use in hospitalised patients.

Kidney

CAUTION

Midarine 100mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Midarine 100mg Injection may be needed. Please consult your doctor.

Liver

CAUTION

Midarine 100mg Injection should be used with caution in patients with liver disease. Dose adjustment of Midarine 100mg Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Midarine 100mg Injection

₹9.63/Injection

Myorelex 100mg Injection

Neon Laboratories Ltd

₹13.4/injection

39% costlier

Suxalin 100mg Injection

Celon Laboratories Ltd

₹25.2/injection

162% costlier

Quick tips

Midarine 100mg Injection is given as an injection into vein under the supervision of a doctor.
It makes you feel dizzy or drowsy. Do not drive until you know how Midarine 100mg Injection affects you.
Your doctor will monitor your blood pressure regularly as the medicine may lead to high blood pressure.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

Acyl Cholines Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Skeletal muscle relaxant- Peripherally acting

Patient concerns

Pain in right arm and calf muscle after recovering during bypass surgery Anyone here Please help me

Dr. Nabajit Talukdar

Interventional Cardiology

When was cabg done

Road accident. Now cured. Is physiotherapy mandatory after removal of POP?? Sir, I met with road accident exactly 63 days ago. Now POP is removed. Still can't walk without walking aid. Doctor told physiotherapy is not required. And not suggested any exercises also for muscle relaxation. Sir, please suggest me , whether I should consult another doctor or exercises not always mandatory

Dr. Akshat Goel

Orthopaedics

Physiotherapy is not mandatory Home exercises are needed for all cases

My husband is having illicit relationship bcoz of that lot of problems. I am very tensed all the time. Please suggest a medicine to calm down. Thank you

Dr. Ambrish Dharmadhikari

Psychiatry

We understand your concernWe are here to helpYou are advised to solve problemAs medicine will help you for temporary periodDiscussing with husband and finding solution will calm you downTill then you can do Jacobson Progressive Muscle Relaxation""http://www.healthline.com/health/what-is-jacobson-relaxation-technique#wholebody-technique3Follow this link to find detailed procedure

Jacobsons relaxation techniques???? What's that I am going through a brk up bt I seriously wAnt to move on nd I am trying my best I hv blocked him in fb so that I can't see his pics or any activities deleted his pics form phn nd deleted his no. Too Bt sometimes when I am alone or sad I am thinking about him small activities memories nd if didn't even remembering at all in dreams I am seeing something wrong That's making me more sad when I wake up I can't concentrate on study bt I rly want to that the dreams r so bad I can't sleep sometimes

Dr. Jyoti Kapoor Madan

Psychiatry

JMR is a method of muscle relaxant which is taught to achieve systematic relaxation in skeletal muscles. This done by a trained psychologist. Relationship issues, heartbreak, infidelity, cheating are all associated with a feeling of rejection or abandonment leading to sadness, anxiety, depression, anger and/ or frustration. Being aware that negative outcomes of relationship don't necessarily mean failure or rejection helps in overcoming the negative thoughts. Compatibility between two individuals is revealed over a period of time and in varying circumstances. Please see a psychiatrist/ psychotherapist if emotional disturbance persists.

FAQs

Q. Why does Midarine 100mg Injection cause bradycardia (abnormally slow heart beat)?

The initial metabolite of Midarine 100mg Injection produces a transient negative chronotropic effect through its stimulation of sinus node muscarinic receptors. Repeated dosing or infusions of Midarine 100mg Injection may lead to bradycardia that is appropriately treated with atropine

Q. Why does Midarine 100mg Injection cause fasciculation (twitching of muscles under the skin)?

Midarine 100mg Injection cause fasciculation by an action on some distal part of motor nerve fibres

Q. Is Midarine 100mg Injection still used?

Midarine 100mg Injection is still used during general anesthesia

Q. Is Midarine 100mg Injection reversible?

Midarine 100mg Injection is a short-acting muscle relaxant which exerts a depolarizing effect at the neuromuscular junction. This effect is not reversible pharmacologically

Q. Is Midarine 100mg Injection is contraindicated in burned patients?

Yes, Midarine 100mg Injection should not be used in burned patients

Q. Does Midarine 100mg Injection cross the placenta?

In normal therapeutic doses, Midarine 100mg Injection does not cross the placental barrier in sufficient amounts.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Suxamethonium. Co Dublin, Ireland: Mercury Pharma International Ltd.; 1990 [revised Jul. 2018]. [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd

Address: Dr. Annie Besant Road, Mumbai - 400 030

Country of origin: India

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2.0 ml in 1 vial

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