Nikoran IV 48 Injection is a medicine used to prevent and treat heart-related chest pain (angina). It is usually prescribed when other heart medicines are not suitable or have not worked. It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart.

Nikoran IV 48 Injection is known as a vasodilator. It is used to treat hypertension and also to manage heart failure

Uses of Nikoran Injection

Treatment of Angina

Benefits of Nikoran Injection

In Treatment of Angina

Nikoran IV 48 Injection helps in prevention as well as treatment of angina. Angina is chest pain that is usually caused by the narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Nikoran IV 48 Injection relaxes and widens the blood vessels so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes thereby improving your ability to exercise and go about your daily life more easily. This medicine needs to be taken regularly to be effective so keep taking it even if you are not having any angina symptoms.

Side effects of Nikoran Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nikoran

Headache
Ulcer
Dizziness
Weakness
Nausea
Vomiting
Palpitations
Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Nikoran Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nikoran Injection works

Nikoran IV 48 Injection is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. It also relaxes coronary artery (that carries blood to heart). This reduces the frequency and severity of angina attacks.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nikoran IV 48 Injection.

Pregnancy

CONSULT YOUR DOCTOR

Nikoran IV 48 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nikoran IV 48 Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Nikoran IV 48 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Nikoran IV 48 Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Nikoran IV 48 Injection may be needed. Please consult your doctor.

Liver

CAUTION

Nikoran IV 48 Injection should be used with caution in patients with severe liver disease. Dose adjustment of Nikoran IV 48 Injection may be needed. Please consult your doctor.

What if you forget to take Nikoran Injection?

If you miss a dose of Nikoran IV 48 Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

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Quick tips

You must continue to take it as advised, usually for a long time.
Nikoran IV 48 Injection may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
Nikoran IV 48 Injection may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.
Do not consume alcohol while taking Nikoran IV 48 Injection as that may cause increased dizziness.
Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Nikoran IV 48 Injection as it may cause low blood pressure.
Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.

Fact Box

Chemical Class

Nicotinamides Derivatives

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Potassium channel opener

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Interventional Cardiology

Related to chest pain angina commonly

Recwntly have heart attack 1 month ago . Can drive 2 wheeler

Dr. Nabajit Talukdar

Interventional Cardiology

can do if no angina etc

Please check the reports and advise what to do? I am a heart patient for last 12 years I am taking medicines Nitroglycerin 2.6 BD NIKORAN 10 OD Clopidogrel 75 OD Ecosprin 75 OD Atorvastin 10 OD Metacard 50 xl OD Flavedon 20 BD Shelcal for calcium OD Above all medicines are prescribed and I am taking this medicines

Dr. Manju Singh

Homeopathy

Your cholesterol levels are high. start exercise in morning and evening for atleast 20 to 30 minutes per day. Include fresh vegetables and fruits in your diet. Increase water intake atleast 2 to 3 lites per day. Take small meals, don't take heavy meals. Avoid fried food or junk food.With this you can start taking: SBL CHOLESTERINUM TRITURATION TABLET 3X2 tablets 2 times a day.

Dr. Aanchal Maheshwari

Ayurveda

As you are a chronic heart patient , so your Allopathic Medicine can be withdrawn as such or suddenly without seeing you. You along with Allopathic Medicine start with Arjun kwath 20 ml twice after meal with water

User feedback

What are you using Nikoran Injection for?

Chest pain (A*

100%

*Chest pain (Angina)

How much was the improvement?

Excellent

67%

Average

33%

FAQs

What is Nikoran IV 48 Injection and what is it used for?

Nikoran IV 48 Injection belongs to a class of medicines known as potassium channel openers. It causes widening of the arteries. This decreases the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients of unstable angina (heart-related chest pain) who cannot take other medicines (beta blockers, calcium channel antagonist) meant for angina.

How long does it take Nikoran IV 48 Injection to start working?

Nikoran IV 48 Injection starts working after about an hour of taking the medicine, but full benefits may be seen only after 4 to 5 days.

What if somebody accidentally takes excess of Nikoran IV 48 Injection?

He or she should be taken to the hospital immediately. The person may experience signs of low blood pressure, which include feeling weak or dizzy. He or she may also experience irregular or fast heart beat.

Can I take Nikoran IV 48 Injection if I am taking aspirin?

You should avoid taking Nikoran IV 48 Injection and aspirin together. Taking these two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor, If you notice blood in your stool or vomit while using Nikoran IV 48 Injection.

Who should not use Nikoran IV 48 Injection?

People who are allergic to Nikoran IV 48 Injection or any of its ingredients should avoid using this medicine. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Nikoran IV 48 Injection. Additionally, patients taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil, and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat) should not use the medication. Your blood pressure may be affected if these medicines are taken with Nikoran IV 48 Injection or if you have low blood volume.

Can Nikoran IV 48 Injection affect my sex life?

No, Nikoran IV 48 Injection does not affect your sex life. However, it is not recommended to take medicines used to treat erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine) while taking Nikoran IV 48 Injection. Taking them together can lead to a serious drop in your blood pressure.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 57.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 198.
National Health Service. Nicorandil; 2019. [Accessed 18 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Nicorandil. [Accessed 19 Mar. 2019] (online) Available from:
Nicorandil [Patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2014. [Accessed 25 Jul. 2023] (online) Available from:

Marketer details

Name: Torrent Pharmaceuticals Ltd

Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Nikoran IV 48 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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