Author Details
Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:15 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Palboxen 125mg Capsule


Product introduction

Palboxen 125mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.

It is an anti cancer medicines

Uses of Palboxen Capsule

Benefits of Palboxen Capsule

In Breast cancer

Palboxen 125mg Capsule helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Palboxen 125mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Side effects of Palboxen Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Palboxen

  • Decreased blood cells (red cells, white cells, and platelets)
  • Fatigue
  • Hair loss
  • Rash
  • Vomiting
  • Diarrhea
  • Nausea
  • Decreased appetite
  • Infection
  • Decreased white blood cell count
  • Stomatitis (Inflammation of the mouth)
  • Anemia (low number of red blood cells)
  • Weakness
  • Fever

How to use Palboxen Capsule

Take this medicine in the dose and duration as advised by your doctor. Palboxen 125mg Capsule is to be taken with food.

How Palboxen Capsule works

Palboxen 125mg Capsule is an anti-cancer medication. Cyclin dependent kinase 4 and 6 (chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6, thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Palboxen 125mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Palboxen 125mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Palboxen 125mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Palboxen 125mg Capsule may cause side effects which could affect your ability to drive.
It may cause fatigue in some people. If this happens, you should exercise caution when driving or using machines.
Kidney
SAFE IF PRESCRIBED
Palboxen 125mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Palboxen 125mg Capsule is recommended.
Liver
CAUTION
Palboxen 125mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Palboxen 125mg Capsule may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Palboxen 125mg Capsule
₹428.57/Capsule
Palbomed 125mg Capsule
Medicamen Biotech Ltd
₹685.71/capsule
74% costlier
Paleno 125mg Capsule
Sun Pharmaceutical Industries Ltd
₹295.19/capsule
25% cheaper
Webace 125mg Capsule
Wembrace Biopharma Pvt. Ltd.
₹262.71/capsule
33% cheaper
Palbenz 125 Capsule
Admac Pharma Ltd
₹428.52/capsule
9% costlier
₹1242/capsule
215% costlier

Quick tips

  • Take it with food, preferably at the same time every day. 
  • If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose
  • Use effective contraception method to prevent pregnancy while taking this medicine.
  • It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you.
  • You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Do not stop taking the medication without talking to your doctor first.

Fact Box

Chemical Class
Pyridinylpiperazines
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Cyclin-Dependent Kinase Inhibitor

Patient concerns

arrow
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
BREAST CANCER , PET REPORT SAYS INFECTION IN SKELETON.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Metastatic breast cancer, send me previous treatment details
arrow

FAQs

What kind of medicine is Palboxen 125mg Capsule?

Palboxen 125mg Capsule is an anti-cancer medicine. Palboxen 125mg Capsule blocks proteins known as cyclin-dependent kinase inhibitors. Blocking these proteins can slow down the growth of cancer cells and delay the progression of the cancer.

How long do I have to take Palboxen 125mg Capsule?

The duration of treatment varies from person to person. Your doctor will decide the number of cycles you need to receive based on your condition, response to treatment and your tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience certain side effects.

Are the side effects of Palboxen 125mg Capsule irreversible?

No, most of the side effects are reversible and disappear when the medicine is stopped. Neutropenia is a well-recognized adverse effect of Palboxen 125mg Capsule in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection while you are taking Palboxen 125mg Capsule. However, this side effect disappears rapidly once you stop taking the medicine.

Does treatment with Palboxen 125mg Capsule require monitoring of blood counts?

Yes, blood tests are important since this medicine can lower your blood counts. The regular blood tests check the effect of Palboxen 125mg Capsule on your blood cells (white blood cells, red blood cells, and platelets). These tests should be done at the beginning of each chemotherapy cycle, on the 15th day of the first 2 cycles, and as clinically indicated.

How should I take Palboxen 125mg Capsule?

Generally, Palboxen 125mg Capsule is taken once daily for 21 consecutive days followed by 7 days off treatment to add up a complete cycle of 28 days. Take this medicine with food and at the same time each day. Swallow the whole capsules. Do not open, chew, or crush them. Do not take the capsules that are broken or cracked. If you vomit after taking Palboxen 125mg Capsule, do not take another dose and continue your regular dosing schedule.

Do I need to use birth control method while using Palboxen 125mg Capsule?

Women of childbearing potential who are receiving Palboxen 125mg Capsule and their partners should use adequate contraceptive methods (e.g. double-barrier contraception such as condom and diaphragm). These methods should be used during therapy and for at least 3 weeks after completing therapy for females. Men who are on Palboxen 125mg Capsule therapy should use birth control methods for at least 14 weeks after completing the therapy.

Does Palboxen 125mg Capsule affect fertility?

Male fertility may be affected during treatment with Palboxen 125mg Capsule. Thus, men may consider sperm preservation prior to beginning therapy with Palboxen 125mg Capsule.

What are the serious side effects of Palboxen 125mg Capsule?

The serious side effects of Palboxen 125mg Capsule include shortness of breath, dizziness, weakness, unusual bleeding or bruising or nosebleeds. It may also cause fever, chills or signs of infection and fast, irregular or pounding heartbeat. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Palbociclib. New York, New York: Pfizer Labs; 2015 [revised 31 Mar. 2017]. [Accessed 25 Jun. 2019] (online) Available from:External Link
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Everest Laboratories
Address: 3-A, Jain Nagar, Meerut City, Uttar Pradesh
Country of origin: India

MRP
9000
Inclusive of all taxes
21.0 capsules in 1 bottle
SOLD OUT
Notify me

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.