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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Pazliz 400 Tablet

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Product introduction

Pazliz 400 Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.

Pazliz 400 Tablet is used to treat different types of cancer

Benefits of Pazliz Tablet

In Kidney cancer

Pazliz 400 Tablet is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Soft tissue sarcoma

Soft tissue sarcoma is a type of sarcoma that develops in tissues such as bone and muscles. Pazliz 400 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.

Side effects of Pazliz Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pazliz

  • Headache
  • Nausea
  • Vomiting
  • Musculoskeletal (bone, muscle or joint) pain
  • Fatigue
  • Change in color of hair
  • Diarrhea
  • High blood pressure
  • Decreased appetite
  • Weight loss
  • Taste change
  • Abnormal skin pigmentation
  • Hair discoloration
  • Tumor pain
  • Breathlessness

How to use Pazliz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pazliz 400 Tablet is to be taken empty stomach.

How Pazliz Tablet works

Pazliz 400 Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (tyrosine kinase) that are responsible for the proliferation of the cancerous cells. It also restricts the growth of new blood vessels within the tumor. This is how it works against cancer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pazliz 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pazliz 400 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Pazliz 400 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Pazliz 400 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pazliz 400 Tablet is safe to use in patients with kidney disease. No dose adjustment of Pazliz 400 Tablet is recommended.
Liver
CAUTION
Pazliz 400 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pazliz 400 Tablet may be needed. Please consult your doctor.
Use of Pazliz 400 Tablet is not advised in patients with moderate to severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pazliz 400 Tablet
₹336.67/Tablet
Votrient 400mg Tablet
Glaxo SmithKline Pharmaceuticals Ltd
₹579/tablet
83% costlier
₹266.53/tablet
16% cheaper
Pazolee 400mg Tablet
Admac Pharma Ltd
₹530/tablet
67% costlier
Pazolit 400mg Tablet
Sun Pharmaceutical Industries Ltd
₹183.33/tablet
42% cheaper
₹350/tablet
11% costlier

Fact Box

Chemical Class
Alkyldiarylamines Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors

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FAQs

Q. Is Pazliz 400 Tablet a chemotherapy medicine?

Pazliz 400 Tablet is not a conventional chemotherapy medicine. It belongs to a class of medicine called a protein kinase inhibitor. Pazliz 400 Tablet works by preventing the activity of proteins that are involved in the growth and spread of cancer cells.

Q. How should I take Pazliz 400 Tablet?

Pazliz 400 Tablet should be taken orally by mouth once a day or as directed by your doctor. Swallow the tablets whole with water, do not break or crush the tablets. This affects the way the medicine is absorbed and may increase the chance of side effects.

Q. Can Pazliz 400 Tablet be taken with food?

Pazliz 400 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after food. If it is taken with food, the dosage may need to be increased. Doing this will in turn cause more side effects.

Q. How will I know if Pazliz 400 Tablet is helping me?

The duration for which you have to continue taking Pazliz 400 Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Q. Are there any food restrictions while I’m taking Pazliz 400 Tablet?

Yes, it is best to avoid grapefruit and grapefruit juice while on Pazliz 400 Tablet, as it may affect how the medicine works in your body. Ask your doctor about any additional foods you should avoid.

Q. How long I have to take Pazliz 400 Tablet?

The duration for which you have to continue taking Pazliz 400 Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Q. What is the most important information I need to know about Pazliz 400 Tablet?

Pazliz 400 Tablet may cause severe or life-threatening liver damage. Inform your doctor if you have or had liver disease. If you experience any of the following symptoms such as discoloration of the skin or eyes (yellowing), dark urine, extreme tiredness, nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, or unusual bleeding or bruising, call your doctor immediately. Your doctor may ask you to take some lab tests before you start taking Votrient. After you start taking Votrient, you may need to take those lab tests at weeks 3, 5, 7 and 9 and then at months 3 and 4. Your doctor may also prescribe additional tests if necessary. Periodic testing should then continue after 4 months.
Related lab tests

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1072-73.
  2. Pazopanib. Research Triangle Park, North Carolina: GlaxoSmithKline; 2009 [revised Apr. 2012]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Khandelwal Laboratories Pvt Ltd
Address: KHANDELWAL LABORATORIES PVT. LTD, 79/87 D.LADPATH, MUMBAI 400 033, INDIA
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Pazliz 400 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP
10100
Inclusive of all taxes
30.0 tablets in 1 bottle
Add to cart

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