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RF 450mg Tablet
Prescription Required
Product introduction
RF 450mg Tablet is an antibiotic, used in the treatment of all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. It may be used alone or in combination with other medicines to fight serious infections.
It is an antibiotic.
It is an antibiotic.
Uses of RF Tablet
Benefits of RF Tablet
In Tuberculosis (TB)
RF 450mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of RF Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of RF
- Low blood platelets
- Dizziness
- Vomiting
- Nausea
- Fever
- Abdominal pain
- Skin rash
- Hepatitis (viral infection of liver)
- Headache
- Chills
- Paradoxical reactions
- Increased aspartate aminotransferase
- Increased alanine aminotransferase
- Increased bilirubin in the blood
How to use RF Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. RF 450mg Tablet is to be taken empty stomach.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with RF 450mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
RF 450mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
RF 450mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
RF 450mg Tablet may cause side effects which could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
Kidney
CAUTION
RF 450mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of RF 450mg Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of RF 450mg Tablet in patients with liver disease. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
RF 450mg Tablet
₹4.14/Tablet
Cavidin 450mg Tablet
Wockhardt Ltd
₹5.8/tablet
40% costlier
Monocin 450mg Tablet
Overseas Healthcare Pvt Ltd
₹3.85/tablet
7% cheaper
Ticin 450mg Tablet
Themis Medicare Ltd
₹4.65/tablet
12% costlier
Rimactane 450mg Tablet
Novartis India Ltd
₹4.24/tablet
2% costlier
Kemorifa 450mg Tablet
Chemo Biological
₹4.3/tablet
4% costlier
Quick tips
- Your doctor has prescribed RF 450mg Tablet to cure your infection and improve symptoms.
- It is best taken on an empty stomach. If you get an upset stomach, try taking it with small portions of food.
- Your urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored.
- Tell your doctor about all other medicines you are taking as RF 450mg Tablet can interact with many medicines.
- Avoid taking hormone-based birth control methods as RF 450mg Tablet may decrease their effectiveness.
- Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills.
Fact Box
Chemical Class
Macrolactams
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
RNA polymerase inhibitors- Rifamycins
Patient concerns
FAQs
Q. Is rifampin a penicillin/amoxicillin/sulfa drug?
No. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has a structure and mechanism of action different from penicillin or amoxicillin (amoxicillin belongs to the class of penicillin antibiotics). The chemical structure and mechanism of action of rifampin is different from sulfa drugs
Q. Is rifampin bacteriostatic or bactericidal?
Rifampin is a bactericidal drug. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for important life processes in the bacteria, thereby killing the bacteria
Q. Is rifampin an inducer or inhibitor?
Rifampin is an inducer (increases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Q. What is R-cin 600 used for?
R-cin 600 is a trade name for active drug rifampin 600 mg. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It is also used in the prevention of meningococcal meningitis and Haemophilus influenza infections. It may also be used in combination with other drugs to treat infections-Brucellosis, Legionnaires disease or serious staphylococcal infections
Q. What is R-cinex/Macox plus/R-cinex 600?
R-cinex and Macox plus are trade names for a combination of active drugs rifampin and isoniazid. It is used in the treatment of tuberculosis. R-cinex 600 and Macox plus contains 600 mg of active drug rifampin and 300 mg of active drug isoniazid
Q. Can I take rifampin with ibuprofen/acetaminophen (Tylenol)?
Rifampin has no known serious drug interaction with ibuprofen or acetaminophen (trade name: Tylenol). Inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does rifampin cause weight gain/weight loss/ hair loss/ constipation/ yeast infection?
No. Changes in body weight, hair loss or triggering constipation are not among the known side effects of rifampin. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has no known effect on causing yeast infections
Q. Does rifampin cause headaches?
Yes. Headache is a possible side effect of rifampin
Q. Does rifampin change urine color/turn urine orange?
Yes. Taking rifampin may change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful
Q. Does rifampin cause liver damage?
Rifampin is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with rifampin. Taking drugs like saquinavir, ritonavir with rifampin can cause severe liver damage. Do consult your doctor if you have any liver problem before taking rifampin.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1550-554.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1213-14.
- Drugs.com. Rifampicin. [Accessed 01 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Sunij Pharma Pvt Ltd
Address: T-1/B National Park, Gulbai Tekra, Ahmedabad – 380 015, (India)
Country of origin: India
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NOT FOR SALE
We do not facilitate sale of this product at present