Unifolin 15mg Tablet is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used in the treatment of methotrexate overdose.

Unifolin 15mg Tablet is used to protect the body cells against the harmful effects of anti-cancer medicines during treatment

Uses of Unifolin Tablet

Prevention of Harmful effects of methotrexate

Benefits of Unifolin Tablet

In Prevention of Harmful effects of methotrexate

Unifolin 15mg Tablet helps protect the body cells against the harmful effects of methotrexate, an anti-cancer medicine. It is a form of vitamin B that is given after 24 hours of methotrexate administration. This makes sure that methotrexate has achieved its anti-cancer effects and also, Unifolin 15mg Tablet will prevent the other side effects such as anemia.

Side effects of Unifolin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Unifolin

No common side effects seen

How to use Unifolin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Unifolin 15mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Unifolin 15mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Unifolin 15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Unifolin 15mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Unifolin 15mg Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Unifolin 15mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Unifolin 15mg Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Unifolin 15mg Tablet

₹47.5/Tablet

Biovorin 15 Tablet

Biochem Pharmaceutical Industries

₹46.03/tablet

3% cheaper

Leucorin Tablet

Samarth Life Sciences Pvt Ltd

₹42.93/tablet

10% cheaper

Covorin 15mg Tablet

Chandra Bhagat Pharma Pvt Ltd

₹77.7/tablet

64% costlier

Leevarin 15 Tablet

Admac Pharma Ltd

₹49.9/tablet

5% costlier

Quick tips

You have been prescribed Unifolin 15mg Tablet to reduce the side effects of the medicine methotrexate.
Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.
Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Unifolin 15mg Tablet may counteract the antiepileptic effects.

Fact Box

Chemical Class

Glutamic acid Derivatives

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Cytoprotective agents- methotrexate

Patient concerns

Any harmful effects of masturbation ?

Dr. Jyoti Arora

Sexology

Dear Mr. PATIENT for sending across your query.Masturbation is sexually health activities don't feel bad about it. It is a harmless expressions.

Best psoriasis health medicine

Dr. Atul Jain

Dermatology

Methotrexate but under supervision of skin specialist

User feedback

Patients taking Unifolin 15mg Tablet

Once A Week

84%

Four Times A *

11%

Once A Day

*Four Times A Day

What are you using Unifolin Tablet for?

Ovarian cance*

100%

*Ovarian cancer

How much was the improvement?

Poor

100%

FAQs

Q. What is Unifolin 15mg Tablet used for?

Unifolin 15mg Tablet is used to prevent harmful effects of methotrexate (a cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Unifolin 15mg Tablet is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. It is also used for the treatment of megaloblastic anemia due to folic acid deficiency and when oral therapy is not feasible.

Q. What is megaloblastic anemia?

Anemia is a blood disorder in which the number of red blood cells (RBCs) that carry oxygen is lower than usual. As a result, your tissues and organs don’t get enough oxygen. Megaloblastic anemia is a form of anemia characterized by very large red blood cells and a decrease in the number of those cells. Usually, megaloblastic anemia is due to vitamin B12 or folic acid deficiency.

Q. How long does it take for Unifolin 15mg Tablet to work?

Unifolin 15mg Tablet starts acting on the body within 20-30 minutes of oral intake. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

Q. What are some of the laboratory tests conducted before or during the treatment with Unifolin 15mg Tablet?

Your doctor will prescribe blood tests to check your levels of serum methotrexate concentration (in case of methotrexate chemotherapy or overdose) to determine the optimal dose and duration of treatment with Unifolin 15mg Tablet. You will also be prescribed a complete blood count to monitor the number of red blood cells (in case of megaloblastic anemia). Along with this, your calcium levels will also be monitored in order to prevent hypercalcemia (excess calcium) since Unifolin 15mg Tablet contains calcium.

Q. What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Unifolin 15mg Tablet?

Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Calcium Folinate. Hurley, Maidenhead: Hospira UK Limited; 1985 [revised Jan. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
DailyMed. Leucovorin calcium. [Accessed 26 Mar. 2019] (online) Available from:

Marketer details

Name: United Biotech Pvt Ltd

Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.