Information about Amifostine

Amifostine Uses

Amifostine is used to prevent dryness in the mouth after radiotherapy of head and neck cancer. It is also used to reduce the harmful effect of chemotherapy on the kidneys during treatment with cisplatin.

Common side effects of Amifostine

Nausea, Vomiting, Decreased blood pressure, Hiccup, Sleepiness, Dizziness, Flushing (sense of warmth in the face, ears, neck and trunk), Fever, Chills
CONTENT DETAILS
Written By
MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
19 Mar 2020 | 06:45 AM (UTC)

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Available Medicine for Amifostine

NatfostNatco Pharma Ltd
931 variant(s)
AmfostedTherdose Pharma Pvt Ltd
45451 variant(s)
M-FostShantha Biotech
25001 variant(s)
AmfosVhb Life Sciences Inc
11251 variant(s)
CytofosSun Pharmaceutical Industries Ltd
10001 variant(s)
AmigetGLS Pharma Ltd.
18001 variant(s)
ChemophosCytogen Pharmaceuticals India Pvt Ltd
19861 variant(s)
EthyfosZee Laboratories
35001 variant(s)
AmiphosDabur India Ltd
19091 variant(s)
EthyolFulford India Ltd
130881 variant(s)

Expert advice for Amifostine

  • Amifostine is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.
  • It is advisable to stay hydrated or drink plenty of fluids before taking medicine.
  • You will be monitored for blood pressure before and after every 5 minutes of infusion.
  • Women who could get pregnant should use a reliable method of contraception to prevent pregnancy while taking this medicine.
  • It may cause a decrease in calcium levels. Your doctor may monitor your calcium levels regularly and prescribe supplements if needed.

Frequently asked questions for Amifostine

Amifostine

Q. Is Amifostine FDA approved?

Yes, it is FDA an approved drug

Q. What is Amifostine used for?

Amifostine is used to reduce toxicity to kidneys associated with cisplatin therapy in patients with advanced ovarian cancer, and in prevention of dry mouth (xerostomia) during radiotherapy for head and neck cancer

Q. How does Amifostine work?

It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol' that binds to and detoxifies the harmful compounds produced by cisplatin. Amifostine does not interfere with the action of cisplatin.

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