Glibenclamide + Metformin + Pioglitazone

Glibenclamide+Metformin+Pioglitazone is used in the treatment of type 2 diabetes mellitus.

Glibenclamide + Metformin + Pioglitazone is a combination of three antidiabetic medicines: Glibenclamide , Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

Hypoglycemia (low blood glucose level), Taste change, Nausea1a, Diarrhea, Stomach pain, Headache, Edema (swelling), Weight gain, Bone fracture, Blurred vision, Respiratory tract infection, Anemia (low number of red blood cells), Vomiting, Flatulence