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Lapatinib
Information about Lapatinib
Lapatinib Uses
Lapatinib is used in the treatment of breast cancer.
How Lapatinib works
Lapatinib is an anti-cancer medication. This works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways.
Common side effects of Lapatinib
Abdominal pain, Back pain, Breathing problems, Constipation, Cough, Diarrhea, Fatigue, Headache, Hot flashes, Increased bilirubin in the blood, Indigestion, Insomnia (difficulty in sleeping), Joint pain, Liver damage, Loss of appetite, Mucosal inflammation, Nausea1a, Pain in extremity, Rash, Stomatitis (Inflammation of the mouth), Vomiting, Weakness, Weight gain
Expert advice for Lapatinib
- It should be taken 1 hour before or 2 hours after the meal, preferably at the same time every day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.