Cholinesterase
Understanding Cholinesterase
What is Cholinesterase?
The Cholinesterase blood test is used to evaluate the levels of two important transmitters in the body viz. acetylcholinesterase (AChE) and pseudocholinesterase (PChE). These transmitters help in the proper functioning of the nervous system. AChE is found in the red blood cells and nerve tissue while PChE is found in the liver. Cholinesterase test is used to diagnose poisoning or toxicity from organophopshates, usually found in pesticides. In addition, this test could be ordered to diagnose liver disease and before giving anaesthesia with succinylcholine.
The normal range of Cholinesterase is 8-18 units/mL. Reduced PChE levels could be indicative of chronic infection, chronic inflammation, poisoning to organophopshates, etc. A less significant decrease is observed in pregnancy and use of birth control pills.
What is Cholinesterase used for?
Cholinesterase is performed in patients who are susceptible to poisoning due to their exposure to chemicals called organophosphates that are present in pesticides. Although rarely, the test can also be done for the diagnosis of any liver disease.
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