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Understanding the Test
Test Measures
FAQ's
References
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Written by
Dr. Anupriya Nautiyal
MD Pathology, MBBS
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Lipid Profile, Non Fasting

Also known as Lipid panel test, Serum lipid profile test, Complete lipid profile test, Cholesterol lipid profile, Fasting lipid profile test
Lipid Profile, Non Fasting Includes 8 testsView All
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Lipid Profile, Non Fasting


What is Lipid Profile, Non Fasting?

The Lipid Profile, Non Fasting helps measure and monitor the amount of different types of lipids, like cholesterol and triglyceride, in the blood. Your doctor may advise this test to determine your overall cardiovascular health if you have risk factors, such as obesity, diabetes, and high blood pressure. It is usually done as a part of routine health checkups. 

Lipids are the types of fats that are used by the body as a source of energy. They are essential for the proper functioning of the body, but their high levels can lead to cardiovascular and heart complications. The Lipid Profile, Non Fasting is a common blood test used to assess the health of your cardiovascular system and aid in the diagnosis and management of lipid disorders. This test measures different types of lipids in your blood, including low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides, total cholesterol, etc.

The Lipid Profile, Non Fasting helps detect conditions like high cholesterol (hyperlipidemia) or low cholesterol (hypolipidemia). Hyperlipidemia is a condition in which your blood contains excessive amounts of lipids. It can lead to plaque buildup (fats and cholesterol) in your arteries and increase the risk of heart disease and stroke. The signs and symptoms may not be evident until a significant blockage or a heart event occurs. Hypolipidemia, while less common, is a condition where your blood does not contain enough lipids, potentially leading to issues with nerve function and an increased risk of infections.

This profile test is suggested for individuals who have a family history of heart conditions, suffer from diabetes, or have high blood pressure to monitor their lipid levels closely. Usually, overnight fasting is not required for this test. You may eat and drink as per your daily routine. 

Test result ranges are approximate and may differ slightly between different labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The results will help them evaluate your medical condition; make recommendations for diet, exercise, or medication; and formulate an overall treatment plan.

NOTE: The Lipid Association of India (LAI) recommends both fasting and non-fasting lipid profiles for managing abnormally elevated cholesterol or fats (lipids) in the blood. However, a non-fasting lipid profile is required to determine the levels of triglyceride fats in the blood post meals.

What is Lipid Profile, Non Fasting used for?

The Lipid Profile, Non Fasting is done:

  • As part of routine health checkups to measure the levels of lipids and cholesterol in the blood.

  • To determine an individual's risk of developing heart conditions, stroke, and peripheral artery disease.

  • To monitor the lipids and cholesterol levels in individuals already diagnosed with high cholesterol or cardiovascular disease to ensure that their treatment plans are effective in maintaining healthy cholesterol levels.

  • To detect early deviations in lipids and cholesterol levels in individuals with a family history of high cholesterol levels or premature heart disease, enabling timely interventions and lifestyle modifications to reduce their risk of cardiovascular complications.

  • To help diagnose other medical conditions, such as liver disease.

What does Lipid Profile, Non Fasting measure?

Contains 8 tests

The Lipid Profile, Non Fasting assesses the level of specific fat molecules called lipids in the blood and helps determine the risk of heart ailments. This test determines the amount of different types of lipids, including total cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides. Lipids play a pivotal role in the functioning of the body. They are crucial components of the cell membranes and hormones, provide cushioning, and are a storehouse of energy. Any alterations in the lipid levels may lead to potential heart ailments, and this makes their monitoring crucial.

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Cholesterol - Total

The Cholesterol - Total test measures the total amount of cholesterol (fats) in your blood. Cholesterol is mainly synthesized in the liver and partially in the intestines. It acts as a building block for cell membranes, is a precursor to vital hormones, and helps produce bile acids that help digest fats. Cholesterol is transported through the blood as lipoproteins: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). An optimal amount of these proteins is necessary for proper body functioning.

Know more about Cholesterol - Total

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Triglycerides

The Triglycerides test measures the amount of triglycerides in the blood and helps evaluate your risk of developing cardiovascular diseases. Triglycerides are a type of fat (lipid) that your body uses as a source of energy. When you consume more calories than your body needs, the excess calories are converted into triglycerides and stored in fat cells for later use. High triglyceride levels can contribute to the hardening and narrowing of arteries, increasing the risk of heart attack, stroke, and other related conditions. 

Know more about Triglycerides

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Cholesterol - HDL

The Cholesterol - HDL test measures the concentration of high-density lipoprotein (HDL) cholesterol in the blood. HDL cholesterol plays a crucial role in maintaining cardiovascular health, as it helps transport excess low-density lipoprotein (LDL) cholesterol from the bloodstream back to the liver for excretion. This process prevents plaque buildup on the blood vessel walls, which can cause them to become narrow and less flexible. Higher HDL cholesterol levels are generally associated with a lower risk of heart problems, such as heart attacks and strokes. By measuring HDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and recommend appropriate preventive or treatment strategies, including lifestyle modifications and medications.

Know more about Cholesterol - HDL

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Cholesterol - LDL

The Cholesterol - LDL test measures the concentration of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol plays an important role in your body. It carries cholesterol from your liver to other parts of the body where it's needed for things like building cell walls and making hormones. However, it is often referred to as "bad" cholesterol because when present in excess in your blood, it can stick to your blood vessel walls leading to the formation of plaque, making them narrow and less flexible. When this happens, it's harder for the blood to flow, which can lead to heart problems, like heart attacks and strokes. By measuring LDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and can recommend appropriate preventive or treatment strategies.

Know more about Cholesterol - LDL

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Very Low Density Lipoprotein

The Very Low Density Lipoprotein test measures the concentration of very-low-density lipoprotein (VLDL) cholesterol in the blood. VLDL cholesterol plays a vital role in the body's metabolic processes. It is produced by the liver and is used to transport triglycerides, a type of fat, from the liver to various tissues throughout the body, where they are either utilized for energy or stored for later use. Though VLDL cholesterol is essential for the body's normal functioning, it is harmful if present in excess amounts. By measuring VLDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and recommend appropriate preventive or treatment strategies.

Know more about Very Low Density Lipoprotein

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Total Cholesterol/HDL Cholesterol Ratio

The Total Cholesterol/HDL Cholesterol Ratio test measures the ratio of total cholesterol and high-density lipoprotein (HDL)/good cholesterol in your blood which is a significant indicator of cardiovascular health. This ratio is calculated by dividing the total cholesterol by the HDL number. A high ratio indicates a higher amount of 'bad' cholesterol relative to 'good' cholesterol, implying a higher risk of developing heart disease. Conversely, a lower ratio implies a higher amount of 'good' cholesterol relative to 'bad' cholesterol, indicating a lower risk.

Know more about Total Cholesterol/HDL Cholesterol Ratio

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LDL/HDL Ratio

An LDL/HDL Ratio test measures the ratio of low-density lipoproteins (LDL) to high-density lipoproteins (HDL) in your blood. These two types of lipoproteins carry cholesterol throughout the body. LDL, often referred to as the 'bad' cholesterol, carries cholesterol to the cells that need it. However, if there is too much LDL cholesterol in the blood, it can combine with other substances and form plaque in the arteries, leading to cardiovascular diseases. On the other hand, HDL, often referred to as the 'good' cholesterol, helps remove other forms of cholesterol, including LDL, from the bloodstream. It transports cholesterol back to the liver, where it is broken down and eliminated from the body, thus reducing the risk of cholesterol buildup and heart disease. The LDL/HDL ratio is a significant indicator of cardiovascular health. A high ratio indicates a higher amount of 'bad' cholesterol relative to 'good' cholesterol, implying a higher risk of developing heart disease. Conversely, a lower ratio implies a higher amount of 'good' cholesterol relative to 'bad' cholesterol, indicating a lower risk.

Know more about LDL/HDL Ratio

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Non HDL Cholesterol

The Non HDL Cholesterol test looks for the “bad” cholesterol particles that are likely to contribute to heart problems. These bad particles include LDL (low-density lipoprotein) cholesterol, VLDL (very-low-density lipoprotein) cholesterol, and remnants of other cholesterol-carrying molecules. Cholesterol is a waxy substance that circulates in your bloodstream and is essential for various bodily functions. However, too much of “bad” types of cholesterol can build up in your arteries and increase the risk of heart conditions. LDL and VLDL cholesterol particles are often referred to as the "bad" cholesterol because they can stick to the walls of your arteries and form plaque, narrowing the arteries and restricting blood flow to your heart. By measuring non-HDL cholesterol, your doctor can assess your risk of heart disease and determine if any interventions or lifestyle changes are needed to protect your heart.

Know more about Non HDL Cholesterol

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Lipid Profile, Non Fasting


Frequently Asked Questions about Lipid Profile, Non Fasting

Q. What is the Lipid Profile, Non Fasting?

The Lipid Profile, Non Fasting is a set of blood tests that tells about the levels of lipids in your blood and helps in the early detection of heart/cardiovascular diseases.

Q. What does the Lipid Profile, Non Fasting measure?

The Lipid Profile, Non Fasting includes tests that measure the levels of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides in your blood.

Q. Why is the Lipid Profile, Non Fasting important for heart health?

The Lipid Profile, Non Fasting is important because high levels of LDL cholesterol or triglycerides or low levels of HDL cholesterol can increase the risk of developing atherosclerosis and other heart-related diseases. Often, high cholesterol is a silent condition without any symptoms. Most people do not even realize they have high cholesterol until they develop serious complications, such as a heart attack or stroke.

Q. Do I need to fast before taking the Lipid Profile, Non Fasting?

No, you do not need to fast before this profile. It can be done at any time of the day irrespective of food intake.

Q. What is the difference between “bad cholesterol” and “good cholesterol”?

“Bad cholesterol” carries cholesterol that can stick to the arterial walls and form plaque, whereas “good cholesterol” takes the cholesterol away from the blood and returns it to the liver.

Q. What is atherosclerosis?

Atherosclerosis is a disease of the arteries that is characterized by plaque formation in the arteries of the walls, leading to heart attack or stroke.

Q. How can I maintain my lipid levels naturally?

You must consult your doctor if your reports show elevated lipid levels. However, you can maintain healthy lipid levels by making a few changes in your lifestyle, such as eating heart-healthy food, managing your body weight by exercising regularly, and avoiding alcohol and smoking.

Q. What foods can cause high cholesterol?

Deep-fried foods, full-fat dairy products, sugary items, cakes and pastries, processed foods, food cooked using unhealthy oils, etc. can increase your cholesterol levels.

Q. What are the most common risk factors for high lipids?

The most common risk factors for high lipids are being over the age of 45 years (men) or over 50 years (women), smoking, obesity, lack of physical activity, high blood pressure, diabetes, family history, or heart disease at an early age (under 55 in men and under 65 in women).
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References

  1. Gofman JW, Lindgren F. The role of lipids and lipoproteins in atherosclerosis. Science. 1950 Feb 17;111(2877):166-71. [Accessed 28 Jun. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/15403115/External Link
  2. Law MR, Wald NJ, Rudnicka AR. Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ. 2003 Jun 28;326(7404):1423. [Accessed 28 Jun. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/12829554/External Link
  3. Wolska A, Remaley AT. Measuring LDL-cholesterol: what is the best way to do it? Curr Opin Cardiol. 2020 Jul.; 35(4):405-411. [Accessed 28 Jun. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360339/External Link
  4. Nauck M, Russell Warnick G, Rifai N. Methods for Measurement of LDL-Cholesterol: A Critical Assessment of Direct Measurement by Homogeneous Assays versus Calculation, Clinical Chemistry. 2002 Feb. 01; 48(2):236-254. [Accessed 28 Jun. 2023]. Available from: https://academic.oup.com/clinchem/article/48/2/236/5641549External Link
  5. M Ridker P. Fasting versus Nonfasting Triglycerides and the Prediction of Cardiovascular Risk: Do We Need to Revisit the Oral Triglyceride Tolerance Test?. Clinical Chemistry. 2008 Jan. 01; 54(1):11-13. [Accessed 28 Jun. 2023]. Available from: https://academic.oup.com/clinchem/article/54/1/11/5628707External Link
  6. Guerrero-Romero F, Villalobos-Molina R, Jiménez-Flores JR, et al. Fasting Triglycerides and Glucose Index as a Diagnostic Test for Insulin Resistance in Young Adults. Archives of Medical Research. 2016 Jul.; 47(5):382-387. [Accessed 28 Jun. 2023]. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0188440916301400External Link
  7. P Neri B, S Frings C. Improved Method for Determination of Triglycerides in Serum. Clinical Chemistry, 1973 Oct. 01; 19(10):1201-1202. [Accessed 28 Jun. 2023]. Available from: https://academic.oup.com/clinchem/article-abstract/19/10/1201/5676688External Link
  8. HDL (Good), LDL (Bad) Cholesterol and Triglycerides [Internet]. Dallas, Texas: American Heart Association; 06 Nov. 2020 [Accessed 28 Jun. 2023]. Available from: https://www.heart.org/en/health-topics/cholesterol/hdl-good-ldl-bad-cholesterol-and-triglycerides#:~:text=HDL%20cholesterol%20can%20be%20thought,and%20passed%20from%20the%20bodyExternal Link
  9. Gordon DJ, Probstfield JL, Garrison RJ, et al. High-density lipoprotein cholesterol and cardiovascular disease. Circulation Research. 1989 Jan. 01; 79(1):8-15. [Accessed 28 Jun. 2023]. Available from: https://www.ahajournals.org/doi/abs/10.1161/01.cir.79.1.8External Link
  10. Wilson PWF, Zech LA, Gregg RE, et al. Estimation of VLDL cholesterol in hyperlipidemia. Clinica Chimica Acta. 1985 Oct. 15; 151(3):285-291. [Accessed 28 Jun. 2023]. Available from: https://www.sciencedirect.com/science/article/abs/pii/0009898185900919External Link
  11. Gordon T, Fisher M, Ernst N, et al. Relation of diet to LDL cholesterol, VLDL cholesterol, and plasma total cholesterol and triglycerides in white adults. The Lipid Research Clinics Prevalence Study. ATVB. 1982 Nov. 01; 2(6):502-512. [Accessed 28 Jun. 2023]. Available from: https://www.ahajournals.org/doi/abs/10.1161/01.ATV.2.6.502External Link

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