Total IgE

A Total IgE test measures the total amount of immunoglobulin E (IgE) in the blood. This test helps diagnose conditions like certain types of infections and immune disorders. It may also be used to make guided treatment decisions in people who have allergy-associated asthma. 

Immunoglobulin E (IgE) is a type of antibody produced by the immune system that helps to defend the body against potential threats or allergies. The body makes many different forms of IgE, each of which is specific to a substance that triggers an immune response. A Total IgE test measures the amount of IgE antibodies in the blood and is the sum of all the forms of IgE. However, this test does not help to identify the specific forms of IgE.

Your doctor may suggest a Total IgE test if you have symptoms of an immune disorder, a parasitic infection, or an allergic reaction from a fungal infection in your lungs. Symptoms may include abdominal pain, cough, diarrhea, dry skin, eczema, hives and swelling, shortness of breath, skin rash, etc. This test may also be prescribed if you have asthma or allergy symptoms, like itchy or watery eyes, congestion, or sneezing. For people with allergy-induced asthma, testing may help to determine the right treatment and suitable dosage.

Usually, overnight fasting is preferred for a Total IgE test. Therefore, avoid eating or drinking anything except water during the fasting period. Also, let your doctor know about any medications you might be taking as some of these medications, such as antihistamines, if taken before this test could affect your test results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. The results will help the doctor determine your medical condition, make recommendations for lifestyle modifications such as diet and exercise, decide whether or not medication will be required to manage your condition, and formulate your overall treatment plan.