Test Detail
Understanding the Test
Test Measures
Interpreting Results
FAQ's
Other Tests
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Dr. Shreya Gupta
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Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests)

Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests) Test Includes 41 testsView All
You need to provide
Blood, Urine
This test is for
Male, Female
Test Preparation
  1. Urine sample must preferably be the midstream urine (part of urine that comes after first and before the last stream). Collect the urine sample in a sealed and sterile container provided by our sample collection professional. Make sure that the container doesn't come in contact with your skin. Please be informed that urine sample is a part of this package, you are required to submit all the samples that are a part of the package during the sample collection itself. Women are advised not to give the sample during the menstrual period unless prescribed.
  2. No special preparation required

Understanding Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests)


What is Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests)?

A fever package extensive is tailored to screen the common cause of fever like dengue, malaria, typhoid and chikungunya. This package offers a widal test, malaria antigen detection test, typhoid IgG and IgM antibody test, chikungunya IgM antibody test, dengue NS1 antigen test, complete blood count test, erythrocyte sedimentation rate test, C-reactive protein test and urine test. You may need this test if you have high fever and weakness, chronic low-grade fever, have signs or symptoms of typhoid fever, dengue fever, malaria or in suspected cases of pyrexia of unknown origin (PUO). This package helps to identify the cause of your fever so that the right treatment can be started.

What is Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests) used for?

-If you are suffering from chronic low-grade fever
-If you have signs or symptoms of typhoid (enteric) fever-like headache, high fever, abdominal pain, diarrhea, weight loss, or skin rashes

-If you have signs and symptoms of dengue such as , high fever, pain behind the eyes, abdominal pain, body aches and skin rash. 

-If you have signs or symptoms of malaria-like fever with shaking chills, headaches
In suspected cases of pyrexia of unknown origin (PUO)

 

 

What does Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests) measure?

Contains 41 tests
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ESR (Erythrocyte Sedimentation Rate)

An ESR test measures the rate at which red blood cells (erythrocytes) settle (sediment) at the bottom of a tube that contains a blood sample in one hour.

When there is any inflammation in the body, certain proteins, mainly fibrinogen, increase in the blood. This increased amount of fibrinogen causes the red blood cells to form a stack (rouleaux formation) that settles quickly due to its high density, leading to an increase in the ESR.

An ESR test is a non-specific measure of inflammation and can be affected by conditions other than inflammation also. This test cannot identify the exact location of the inflammation in your body or what is causing it. Hence, an ESR test is usually prescribed along with a few other tests to identify or treat possible health concerns.

Know more about ESR (Erythrocyte Sedimentation Rate)

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Dengue Fever NS1 Antigen

A Dengue Fever NS1 Antigen test measures the NS-1 protein of the dengue virus. This protein is secreted into the blood during the infection, hence it can be detected during the early stages of the infection only. This test is sensitive for 7 days after the symptoms are experienced. After day 7, the Dengue Fever NS1 Antigen test is not recommended. 

If left untreated, dengue fever may progress to a severe form such as dengue hemorrhagic fever or dengue shock syndrome.

Dengue hemorrhagic fever (DHF) can go to a higher grade. It might also include variable bleeding manifestations like bleeding from the nose, vomiting blood, passing blood in the stool, difficulty breathing, and cold clammy skin, especially in the extremities. During the second phase, the virus may attack blood vessels, causing capillaries to leak fluid into the space around the lungs (pleural effusion) or the abdominal cavity (ascites).

Dengue shock syndrome (DSS) is a severe complication of dengue fever that is caused when the body's immune system overreacts to the dengue virus. It can lead to a sudden drop in blood pressure and dehydration, and if not managed timely, it may lead to multiple organ failures. 

There is no specific treatment for dengue, but early diagnostic testing, such as the dengue NS1 antigen can prevent the advancement of dengue to its complicated forms.

Know more about Dengue Fever NS1 Antigen

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CBC (Complete Blood Count)

A CBC (Complete Blood Count) test evaluates red blood cells (RBCs), white blood cells (WBCs}, and platelets. Each of these blood cells performs essential functions–RBCs carry oxygen from your lungs to the various body parts, WBCs help fight infections and other diseases, and platelets help your blood to clot–so determining their levels can provide significant health information. A CBC test also determines the hemoglobin level, a protein in RBC that carries oxygen from the lungs to the rest of your body. Evaluating all these components together can provide important information about your overall health.

Know more about CBC (Complete Blood Count)

  • Absolute Lymphocyte Count

  • An Absolute Lymphocyte Count test measures the total number of lymphocytes in the blood. Lymphocytes are a type of white blood cells that play an important role in your immune system and help your body fight disease and infection. There are two main types of lymphocytes:

    • T lymphocytes (T cells): T cells control your body’s immune system response and directly attack and kill infected cells and tumor cells.

    • B lymphocytes (B cells): B cells make antibodies. Antibodies are proteins that target viruses, bacteria, and other foreign pathogens.

    Lymphocytes help your immune system remember every antigen (a foreign substance) it comes in contact with. After an encounter, some lymphocytes turn into memory cells. When these memory cells run into an antigen again, they recognize it and quickly respond. It is also the reason why getting vaccinated helps prevent certain diseases.

  • Absolute Neutrophil Count

  • An Absolute Neutrophil Count test measures the percentage of neutrophils per microliter of blood. Neutrophils are a type of WBC and play an integral part in the body's immune system. They help fight off bacterial infections in the body by identifying and destroying foreign invaders, such as disease-causing microorganisms. 

  • Differential leukocyte Count

  • There are five types of WBCs: neutrophils, lymphocytes, monocytes, eosinophils, and basophils. A Differential leukocyte Count test measures the percentage of each type of WBC in the blood. Leukocytes or WBCs are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

    This further contains

    • Differential Neutrophil Count
    • Differential Lymphocyte Count
    • Differential Monocyte Count
    • Differential Eosinophil Count
    • Differential Basophil Count
  • Red Blood Cell Count

  • A Red Blood Cell Count test measures the total number of red blood cells in your blood. RBCs are the most abundant cells in the blood with an average lifespan of 120 days. These cells are produced in the bone marrow and destroyed in the spleen or liver. Their primary function is to help carry oxygen from the lungs to different body parts. The normal range of RBC count can vary depending on age, gender, and the equipment and methods used for testing.

  • Hb (Hemoglobin)

  • A Hb (Hemoglobin) test measures the concentration of hemoglobin protein in your blood. Hemoglobin is made up of iron and globulin proteins. It is an essential part of RBCs and is critical for oxygen transfer from the lungs to all body tissues. Most blood cells, including RBCs, are produced regularly in your bone marrow. The Hb test is a fundamental part of a complete blood count (CBC) and is used to monitor blood health, diagnose various blood disorders, and assess your response to treatments if needed.

  • Platelet Count

  • A Platelet Count test measures the average number of platelets in the blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days. 

    Platelets help stop the bleeding, whenever there is an injury or trauma to a tissue or blood vessel, by adhering and accumulating at the injury site and releasing chemical compounds that stimulate the gathering of more platelets. A loose platelet plug is formed at the site of injury and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps, including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this step, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding. 

  • Total Leukocyte Count

  • A Total Leukocyte Count test measures the numbers of all types of leukocytes, namely neutrophil, lymphocyte, monocyte, eosinophil, and basophil, in your blood. Leukocytes or WBCs are an essential part of our immune system. These cells are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

  • Absolute Basophil Count

  • An Absolute Basophil Count test measures the total number of basophils in the blood. Basophils are small, spherically-shaped cells that originate from bone marrow and make up almost 1% of the total white blood cells in the body. They attack a foreign substance and release proteins like histamine and heparin to destroy harmful substances, such as allergens, pathogens, or parasites. Histamine helps widen the blood vessels and make space for more immune cells to come to the site of infection or injury, whereas heparin acts as a blood-thinning agent and helps to avoid blood clotting at that site.

  • Absolute Monocyte Count

  • An Absolute Monocyte Count test measures the total number of monocytes in the blood. Monocytes are a type of WBC that originate from bone marrow and travel to different tissues via the blood. Once they are inside the tissue, these cells get converted to macrophages (a type of cell that digest harmful substances). Monocytes are the second line of defense mechanism of the human body after neutrophils. These cells are also responsible for the removal of injured or dead cells, microorganisms, and other insoluble particles from the blood. 

  • Absolute Eosinophil Count

  • An Absolute Eosinophil Count test measures the number of eosinophils in the blood and provides important information about the functioning of the immune system. Eosinophils originate from bone marrow and have a lifespan of 8-18 hours. These cells are involved in fighting certain types of infections and responding to allergic reactions in the body. The eosinophils have varied functions including the physiological role in organ formation, such as the development of post-gestational mammary glands. Other functions of these cells include movement to the inflammation areas, trapping substances, killing cells, and bactericidal and antiparasitic activities. They also help in the treatment of immediate allergic reactions and modulation of inflammatory responses. By measuring the number of eosinophils in the blood, this test provides important information about the functioning of the immune system.

  • Hematocrit

  • A Hematocrit test measures the proportion of red blood cells (RBCs) in your blood as a percentage of the total blood volume. It is a crucial part of a complete blood count (CBC) and helps in assessing your blood health. RBCs are responsible for carrying oxygen from the lungs to different parts of the body. The hematocrit test provides valuable information about your blood's oxygen-carrying capacity.

    Higher-than-normal amounts of RBCs produced by the bone marrow can cause the hematocrit to increase, leading to increased blood density and slow blood flow. On the other hand, lower-than-normal hematocrit can be caused by low production of RBCs, reduced lifespan of RBCs in circulation, or excessive bleeding, leading to a reduced amount of oxygen being transported by RBCs. Monitoring your hematocrit levels is essential for diagnosing and managing various blood-related disorders.

  • Mean Corpuscular Volume

  • A Mean Corpuscular Volume test measures the average size of your red blood cells, which carry oxygen through your body. This test tells whether your RBCs are uniform or vary significantly in size.

  • Mean Corpuscular Hemoglobin

  • An MCH test measures the average amount of hemoglobin in a single red blood cell (RBC). Hemoglobin is an iron-containing protein in RBCs, and its major function is to transport oxygen from the lungs to all body parts. This test provides information about how much oxygen is being delivered to the body by a certain number of RBCs.

  • Mean Corpuscular Hemoglobin Concentration

  • An MCHC test measures the average amount of hemoglobin in a given volume of RBCs. MCHC is calculated by dividing the amount of hemoglobin by hematocrit (volume of blood made up of RBCs) and then multiplying it by 100. 

  • Mean Platelet Volume

  • An MPV test measures the average size of the platelets in your blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days. 

    Platelets help stop bleeding whenever there is an injury or trauma to a tissue or blood vessel by adhering and accumulating at the injury site, and by releasing chemical compounds that stimulate the gathering of more platelets. After these steps, a loose platelet plug is formed at the site of injury, and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or are not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding. 

  • PDW

  • RDW CV

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CRP (C-Reactive Protein) - Quantitative

A CRP test measures the levels of CRP protein in your body. This test helps detect the presence of inflammation in the body. It is a non-specific test as it cannot diagnose a condition by itself or determine its exact location or cause. 

CRP is an acute phase reactant protein that is produced by the liver in response to an inflammation in the body. This inflammation may be due to tissue injury, infection, autoimmune diseases, or cancer. CRP levels are often increased before the onset of other symptoms of inflammation such as pain, redness, fever, or swelling. These levels fall as the inflammation subsides.

Know more about CRP (C-Reactive Protein) - Quantitative

Malarial Antigen (Vivax & Falciparum) Detection

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Widal Test (Slide Agglutination)

A Widal Test (Slide Agglutination) helps detect antibodies in the blood against typhoid-causing bacteria called Salmonella typhi.

Know more about Widal Test (Slide Agglutination)

Peripheral Smear Examination

Chikungunya IgM

Typhidot IgG & IgM

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Urine R/M (Urine Routine & Microscopy)

A Urine R/M (Urine Routine & Microscopy) test involves gross, chemical, and microscopic evaluation of the urine sample.

  1. Gross examination: It involves the visual examination of the urine sample for color and appearance. Normally, the urine color ranges from colorless or pale yellow to deep amber, depending on the urine’s concentration. Things such as medications, supplements, and some foods such as beetroot can affect the color of your urine. However, unusual urine color can also be a sign of disease.

    In appearance, the urine sample may be clear or cloudy. A clear appearance is indicative of healthy urine. However, the presence of red blood cells, white blood cells, bacteria, etc. may result in cloudy urine, indicating conditions such as dehydration, UTIs, kidney stones, etc. Some other factors such as sperm and skin cells may also result in a cloudy appearance but are harmless.

  2. Chemical examination: It examines the chemical nature of the urine sample using special test strips called dipsticks. These test strips are dipped into the urine sample and they change color when they come in contact with specific substances. The degree of color change gives an estimate of the amount of the substance present. Some of the common things detected include protein, urine pH, ketones, glucose, specific gravity, blood, nitrites, and urobilinogen among others.

  3. Microscopic examination: It involves the examination of the urine sample under the microscope for casts, crystals, cells, bacteria, and yeast. 

Know more about Urine R/M (Urine Routine & Microscopy)

  • Urobilinogen

  • Ketone

  • Nitrite

  • Colour

  • Appearance

  • Specific Gravity

  • Epithelial Cell

  • Casts

  • Crystals

  • Protein Urine

  • Ph for Urine

  • Urine Glucose

Interpreting Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests) results


Interpretations

 

  • Positive Salmonella typhi IgM test suggests recent infection with bacteria Salmonella Typhi causing typhoid fever 

  • Negative Salmonella typhi IgM test usually indicates no infection with the bacteria

 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests)


Frequently Asked Questions about Fever Package Extensive (includes Dengue, Malaria, Typhoid & Chikungunya tests)

Q. Is there any risk associated with this test?

There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.

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